STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EEI87109.1HAD hydrolase, family IB; COG: COG0560; InterPro: IPR006385. (245 aa)    
Predicted Functional Partners:
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
  
 0.958
rdgB
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.797
EEI87108.1
Hypothetical protein.
       0.789
EEI87107.1
Phosphodiesterase family protein; COG: COG0622; Pfam: PF00149; InterPro: IPR000979.
       0.765
EEI87100.1
Hypothetical protein.
 
     0.685
relA
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
  0.660
EEI85441.1
DnaD domain protein; Pfam: PF04271; InterPro: IPR006343.
  
     0.654
glcK
ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600.
     
 0.617
EEI87101.1
Pseudouridine synthase, RluA family; COG: COG0564; Pfam: PF01479,PF00849; InterPro: IPR006225; Belongs to the pseudouridine synthase RluA family.
       0.609
EEI87103.1
Response regulator receiver domain protein; COG: COG0745; Pfam: PF00072,PF00486; InterPro: IPR001789.
       0.609
Your Current Organism:
Anaerococcus lactolyticus
NCBI taxonomy Id: 525254
Other names: A. lactolyticus ATCC 51172, Anaerococcus lactolyticus ATCC 51172, Anaerococcus lactolyticus str. ATCC 51172, Anaerococcus lactolyticus strain ATCC 51172
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