Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
xpnpep1Creatinase; COG: COG0006; Pfam: PF01321,PF00557; InterPro: IPR000994. (589 aa)    
Predicted Functional Partners:
hprK
HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...]
       0.822
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
       0.822
nifJ-2
Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR011895.
     
 0.809
EEI85742.1
Putative ComE operon protein 2; COG: COG2131; Pfam: PF00383; InterPro: IPR016473.
  
  
 0.795
EEI86375.1
Rubredoxin; COG: COG1960; Pfam: PF02771,PF02770,PF00441,PF00766,PF00301; InterPro: IPR013764.
  
 0.782
EEI85599.1
Putative phage-associated protein, HI1409 family; COG: COG1960; Pfam: PF02771,PF02770,PF00441,PF00766; InterPro: IPR013764.
  
 0.782
EEI86104.1
Peptidase M16 inactive domain protein; COG: COG1026; Pfam: PF00675,PF05193,PF08367; InterPro: IPR013578.
   
 
 0.752
nemA
Pyridine nucleotide-disulfide oxidoreductase; COG: COG1902; Pfam: PF00724,PF07992,PF00070; InterPro: IPR013785.
  
 0.749
nifJ
Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895.
     
 0.727
gatA
aspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
   
   0.694
Your Current Organism:
Anaerococcus lactolyticus
NCBI taxonomy Id: 525254
Other names: A. lactolyticus ATCC 51172, Anaerococcus lactolyticus ATCC 51172, Anaerococcus lactolyticus str. ATCC 51172, Anaerococcus lactolyticus strain ATCC 51172
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