STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pheTphenylalanine--tRNA ligase, beta subunit; COG: COG0072; Pfam: PF01588,PF03483,PF03484,PF03147; InterPro: IPR004532; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (795 aa)    
Predicted Functional Partners:
pheS
phenylalanine--tRNA ligase, alpha subunit; COG: COG0016; Pfam: PF02912,PF01409; InterPro: IPR002319; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
 
 0.999
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 
 0.981
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.978
argS
arginine--tRNA ligase; COG: COG0018; Pfam: PF03485,PF00750,PF05746; InterPro: IPR001278.
 
  
 0.977
EEI85375.1
Phosphoribosylformylglycinamidine synthase; COG: COG0046; Pfam: PF02769; InterPro: IPR010141.
  
  
 0.973
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
  
 
 0.962
leuS
leucine--tRNA ligase; COG: COG0495; Pfam: PF09334,PF08264; InterPro: IPR002302; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.955
lysS
lysine--tRNA ligase; COG: COG1190; Pfam: PF01336,PF00152,PF01588; InterPro: IPR002313; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.936
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.930
EEI85214.1
Putative methionine--tRNA ligase, beta subunit; COG: COG0073; Pfam: PF01588; InterPro: IPR012340.
  
 
 0.926
Your Current Organism:
Anaerococcus lactolyticus
NCBI taxonomy Id: 525254
Other names: A. lactolyticus ATCC 51172, Anaerococcus lactolyticus ATCC 51172, Anaerococcus lactolyticus str. ATCC 51172, Anaerococcus lactolyticus strain ATCC 51172
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.