Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
metNABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa)    
Predicted Functional Partners:
EEI86673.1
NLPA lipoprotein; COG: COG1464; Pfam: PF03180; InterPro: IPR004872.
 
 0.999
EEI86674.1
ABC transporter, permease protein; COG: COG2011; Pfam: PF00528; InterPro: IPR000515.
 
 0.999
EEI86672.1
NLPA lipoprotein; COG: COG1464; Pfam: PF03180; InterPro: IPR004872; Belongs to the nlpA lipoprotein family.
 
 0.997
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.799
EEI86676.1
Amidohydrolase; COG: COG1473; Pfam: PF01546,PF07687; InterPro: IPR017439.
       0.789
EEI85620.1
Hypothetical protein; COG: COG0620.
  
 
 0.720
hom
Homoserine dehydrogenase; COG: COG0460; Pfam: PF03447,PF00742; InterPro: IPR001342.
   
 
 0.709
cysK
Cysteine synthase A; COG: COG0031; Pfam: PF00291; InterPro: IPR005859.
    
 0.694
EEI86971.1
Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367.
   
   0.681
EEI85961.1
Transcriptional regulator, Crp/Fnr family; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367.
   
   0.681
Your Current Organism:
Anaerococcus lactolyticus
NCBI taxonomy Id: 525254
Other names: A. lactolyticus ATCC 51172, Anaerococcus lactolyticus ATCC 51172, Anaerococcus lactolyticus str. ATCC 51172, Anaerococcus lactolyticus strain ATCC 51172
Server load: low (26%) [HD]