| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEI86577.1 | EEI86583.1 | HMPREF0072_0835 | HMPREF0072_0841 | Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | Prokaryotic diacylglycerol kinase; COG: COG0818; Pfam: PF01219; InterPro: IPR000829. | 0.818 |
| EEI86577.1 | EEI86585.1 | HMPREF0072_0835 | HMPREF0072_0843 | Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | 0.824 |
| EEI86577.1 | cdd | HMPREF0072_0835 | HMPREF0072_0840 | Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.792 |
| EEI86577.1 | era | HMPREF0072_0835 | HMPREF0072_0839 | Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.824 |
| EEI86577.1 | glyQ | HMPREF0072_0835 | HMPREF0072_0837 | Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | glycine--tRNA ligase, alpha subunit; COG: COG0752; Pfam: PF02091; InterPro: IPR002310. | 0.794 |
| EEI86577.1 | glyS | HMPREF0072_0835 | HMPREF0072_0836 | Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | glycine--tRNA ligase, beta subunit; COG: COG0751; Pfam: PF02092; InterPro: IPR015944. | 0.860 |
| EEI86577.1 | guaA | HMPREF0072_0835 | HMPREF0072_0834 | Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.801 |
| EEI86577.1 | ppdK | HMPREF0072_0835 | HMPREF0072_2063 | Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | Pyruvate, phosphate dikinase; COG: COG0574; Pfam: PF01326,PF00391,PF02896; InterPro: IPR010121; Belongs to the PEP-utilizing enzyme family. | 0.737 |
| EEI86577.1 | recO | HMPREF0072_0835 | HMPREF0072_0838 | Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.818 |
| EEI86577.1 | ybeY | HMPREF0072_0835 | HMPREF0072_0842 | Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.789 |
| EEI86583.1 | EEI86577.1 | HMPREF0072_0841 | HMPREF0072_0835 | Prokaryotic diacylglycerol kinase; COG: COG0818; Pfam: PF01219; InterPro: IPR000829. | Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | 0.818 |
| EEI86583.1 | EEI86585.1 | HMPREF0072_0841 | HMPREF0072_0843 | Prokaryotic diacylglycerol kinase; COG: COG0818; Pfam: PF01219; InterPro: IPR000829. | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | 0.866 |
| EEI86583.1 | cdd | HMPREF0072_0841 | HMPREF0072_0840 | Prokaryotic diacylglycerol kinase; COG: COG0818; Pfam: PF01219; InterPro: IPR000829. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.822 |
| EEI86583.1 | era | HMPREF0072_0841 | HMPREF0072_0839 | Prokaryotic diacylglycerol kinase; COG: COG0818; Pfam: PF01219; InterPro: IPR000829. | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.878 |
| EEI86583.1 | glyQ | HMPREF0072_0841 | HMPREF0072_0837 | Prokaryotic diacylglycerol kinase; COG: COG0818; Pfam: PF01219; InterPro: IPR000829. | glycine--tRNA ligase, alpha subunit; COG: COG0752; Pfam: PF02091; InterPro: IPR002310. | 0.821 |
| EEI86583.1 | glyS | HMPREF0072_0841 | HMPREF0072_0836 | Prokaryotic diacylglycerol kinase; COG: COG0818; Pfam: PF01219; InterPro: IPR000829. | glycine--tRNA ligase, beta subunit; COG: COG0751; Pfam: PF02092; InterPro: IPR015944. | 0.822 |
| EEI86583.1 | guaA | HMPREF0072_0841 | HMPREF0072_0834 | Prokaryotic diacylglycerol kinase; COG: COG0818; Pfam: PF01219; InterPro: IPR000829. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.827 |
| EEI86583.1 | recO | HMPREF0072_0841 | HMPREF0072_0838 | Prokaryotic diacylglycerol kinase; COG: COG0818; Pfam: PF01219; InterPro: IPR000829. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.902 |
| EEI86583.1 | ybeY | HMPREF0072_0841 | HMPREF0072_0842 | Prokaryotic diacylglycerol kinase; COG: COG0818; Pfam: PF01219; InterPro: IPR000829. | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.990 |
| EEI86585.1 | EEI86577.1 | HMPREF0072_0843 | HMPREF0072_0835 | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | 0.824 |