| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEI86542.1 | eda | HMPREF0072_0931 | HMPREF0072_0944 | Putative 2-keto-3-deoxygluconate transporter; Pfam: PF03812; InterPro: IPR004684. | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | 0.808 |
| eda | EEI86542.1 | HMPREF0072_0944 | HMPREF0072_0931 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Putative 2-keto-3-deoxygluconate transporter; Pfam: PF03812; InterPro: IPR004684. | 0.808 |
| eda | gap | HMPREF0072_0944 | HMPREF0072_0439 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.806 |
| eda | glvC | HMPREF0072_0944 | HMPREF0072_1062 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | PTS system, glucose-like IIB component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR003352. | 0.839 |
| eda | kdgK | HMPREF0072_0944 | HMPREF0072_0934 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Kinase, PfkB family; COG: COG0524; Pfam: PF00294; InterPro: IPR011611. | 0.967 |
| eda | nifJ | HMPREF0072_0944 | HMPREF0072_0477 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | 0.894 |
| eda | nifJ-2 | HMPREF0072_0944 | HMPREF0072_0478 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR011895. | 0.894 |
| eda | pgi | HMPREF0072_0944 | HMPREF0072_1070 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.827 |
| eda | ptbA-2 | HMPREF0072_0944 | HMPREF0072_1060 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | PTS system, glucose subfamily, IIA component; COG: COG2190; Pfam: PF00358; InterPro: IPR001127. | 0.907 |
| eda | pyk | HMPREF0072_0944 | HMPREF0072_0070 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887,PF00391; InterPro: IPR001697; Belongs to the pyruvate kinase family. | 0.903 |
| eda | tpiA | HMPREF0072_0944 | HMPREF0072_0437 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.899 |
| gap | eda | HMPREF0072_0439 | HMPREF0072_0944 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | 0.806 |
| gap | glvC | HMPREF0072_0439 | HMPREF0072_1062 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | PTS system, glucose-like IIB component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR003352. | 0.461 |
| gap | kdgK | HMPREF0072_0439 | HMPREF0072_0934 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Kinase, PfkB family; COG: COG0524; Pfam: PF00294; InterPro: IPR011611. | 0.622 |
| gap | nifJ | HMPREF0072_0439 | HMPREF0072_0477 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | 0.750 |
| gap | nifJ-2 | HMPREF0072_0439 | HMPREF0072_0478 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR011895. | 0.750 |
| gap | pgi | HMPREF0072_0439 | HMPREF0072_1070 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.984 |
| gap | ptbA-2 | HMPREF0072_0439 | HMPREF0072_1060 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | PTS system, glucose subfamily, IIA component; COG: COG2190; Pfam: PF00358; InterPro: IPR001127. | 0.601 |
| gap | pyk | HMPREF0072_0439 | HMPREF0072_0070 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887,PF00391; InterPro: IPR001697; Belongs to the pyruvate kinase family. | 0.983 |
| gap | tpiA | HMPREF0072_0439 | HMPREF0072_0437 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.999 |