Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemZPutative coproporphyrinogen dehydrogenase HemZ; COG: COG0635; Pfam: PF04055; InterPro: IPR006638. (433 aa)    
Predicted Functional Partners:
hemN
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
0.805
argS
arginine--tRNA ligase; COG: COG0018; Pfam: PF03485,PF00750,PF05746; InterPro: IPR001278.
   
    0.791
pepD
Xaa-His dipeptidase; COG: COG2195; Pfam: PF01546,PF07687; InterPro: IPR001160.
       0.788
EEI86455.1
Hypothetical protein.
       0.631
miaB
tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
 
  
 0.626
yqeV
tRNA methylthiotransferase YqeV; COG: COG0621; Pfam: PF00919,PF04055; InterPro: IPR005839.
 
  
 0.615
EEI86456.1
Hypothetical protein.
 
     0.607
sps1
Kinase domain protein; COG: COG0515; Pfam: PF00069,PF03793; InterPro: IPR002290.
    
  0.569
nifJ
Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895.
     
 0.528
nifJ-2
Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR011895.
     
 0.528
Your Current Organism:
Anaerococcus lactolyticus
NCBI taxonomy Id: 525254
Other names: A. lactolyticus ATCC 51172, Anaerococcus lactolyticus ATCC 51172, Anaerococcus lactolyticus str. ATCC 51172, Anaerococcus lactolyticus strain ATCC 51172
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