Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EEI86382.1Hypothetical protein; COG: COG1912; Pfam: PF01887; InterPro: IPR002747. (278 aa)    
Predicted Functional Partners:
EEI86381.1
Hypothetical protein; COG: COG4720; Pfam: PF07155; InterPro: IPR009825.
 
     0.918
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
    
  0.895
sdcBB
Cobalt transport family protein; COG: COG0619.
 
     0.895
EEI86380.1
ABC transporter, ATP-binding protein; COG: COG1122; Pfam: PF00005; InterPro: IPR003593.
 
     0.873
EEI86490.1
Hypothetical protein; COG: COG0619.
 
     0.710
thyX
Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
    
  0.656
cmk
Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136.
    
  0.649
ppaC
DHHA2 domain protein; COG: COG1227; Pfam: PF00571,PF07085,PF02833; InterPro: IPR000644.
    
  0.643
cinA
Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994,PF02464; InterPro: IPR008135; Belongs to the CinA family.
    
  0.634
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG: COG0138; Pfam: PF02142,PF01808; InterPro: IPR002695.
    
  0.630
Your Current Organism:
Anaerococcus lactolyticus
NCBI taxonomy Id: 525254
Other names: A. lactolyticus ATCC 51172, Anaerococcus lactolyticus ATCC 51172, Anaerococcus lactolyticus str. ATCC 51172, Anaerococcus lactolyticus strain ATCC 51172
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