| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEI85278.1 | gloA | HMPREF0072_2196 | HMPREF0072_1708 | Nitroreductase family protein; COG: COG0778; Pfam: PF00881; InterPro: IPR016446; Belongs to the flavin oxidoreductase frp family. | Glyoxalase family protein; COG: COG0346; Pfam: PF00903; InterPro: IPR004360. | 0.760 |
| EEI85278.1 | tadA | HMPREF0072_2196 | HMPREF0072_1992 | Nitroreductase family protein; COG: COG0778; Pfam: PF00881; InterPro: IPR016446; Belongs to the flavin oxidoreductase frp family. | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.669 |
| EEI85892.1 | gloA | HMPREF0072_1516 | HMPREF0072_1708 | Nitroreductase family protein; COG: COG0778; Pfam: PF00881; InterPro: IPR000415. | Glyoxalase family protein; COG: COG0346; Pfam: PF00903; InterPro: IPR004360. | 0.760 |
| EEI85892.1 | tadA | HMPREF0072_1516 | HMPREF0072_1992 | Nitroreductase family protein; COG: COG0778; Pfam: PF00881; InterPro: IPR000415. | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.669 |
| deoD | hpt | HMPREF0072_0411 | HMPREF0072_1871 | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.945 |
| deoD | tadA | HMPREF0072_0411 | HMPREF0072_1992 | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.733 |
| deoD | tilS | HMPREF0072_0411 | HMPREF0072_1870 | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.730 |
| gloA | EEI85278.1 | HMPREF0072_1708 | HMPREF0072_2196 | Glyoxalase family protein; COG: COG0346; Pfam: PF00903; InterPro: IPR004360. | Nitroreductase family protein; COG: COG0778; Pfam: PF00881; InterPro: IPR016446; Belongs to the flavin oxidoreductase frp family. | 0.760 |
| gloA | EEI85892.1 | HMPREF0072_1708 | HMPREF0072_1516 | Glyoxalase family protein; COG: COG0346; Pfam: PF00903; InterPro: IPR004360. | Nitroreductase family protein; COG: COG0778; Pfam: PF00881; InterPro: IPR000415. | 0.760 |
| gloA | tadA | HMPREF0072_1708 | HMPREF0072_1992 | Glyoxalase family protein; COG: COG0346; Pfam: PF00903; InterPro: IPR004360. | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.777 |
| hpt | deoD | HMPREF0072_1871 | HMPREF0072_0411 | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | 0.945 |
| hpt | pyrD | HMPREF0072_1871 | HMPREF0072_0256 | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. | 0.661 |
| hpt | tadA | HMPREF0072_1871 | HMPREF0072_1992 | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.714 |
| hpt | tilS | HMPREF0072_1871 | HMPREF0072_1870 | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.993 |
| hpt | upp | HMPREF0072_1871 | HMPREF0072_2177 | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.536 |
| pyrD | hpt | HMPREF0072_0256 | HMPREF0072_1871 | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.661 |
| pyrD | tadA | HMPREF0072_0256 | HMPREF0072_1992 | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.675 |
| pyrD | udk | HMPREF0072_0256 | HMPREF0072_1994 | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. | Uridine kinase; COG: COG0572; Pfam: PF00485; InterPro: IPR000764. | 0.739 |
| pyrD | upp | HMPREF0072_0256 | HMPREF0072_2177 | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.784 |
| tadA | EEI85278.1 | HMPREF0072_1992 | HMPREF0072_2196 | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | Nitroreductase family protein; COG: COG0778; Pfam: PF00881; InterPro: IPR016446; Belongs to the flavin oxidoreductase frp family. | 0.669 |