STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EEI85450.1Oxidoreductase NAD-binding domain protein; COG: COG0543; Pfam: PF00970,PF00175; InterPro: IPR012165. (280 aa)    
Predicted Functional Partners:
gltA-2
Glutamate synthase (NADPH), homotetrameric; COG: COG0493; Pfam: PF07992,PF00070; InterPro: IPR006004.
 
 0.999
pyrD
Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate.
 
 0.991
nifJ
Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895.
  
 
 0.949
nifJ-2
Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR011895.
  
 
 0.949
EEI87225.1
Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 
 0.926
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.917
pyrF
Orotidine 5'-phosphate decarboxylase; COG: COG0284; Pfam: PF00215; InterPro: IPR011995; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.916
pyrB
Aspartate carbamoyltransferase; COG: COG0540; Pfam: PF02729,PF00185; InterPro: IPR002082; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.898
EEI85575.1
Putative iron-sulfur cluster-binding protein; COG: COG1139; Pfam: PF02589,PF00037,PF02754; InterPro: IPR004017.
  
 0.832
nqr
Flavin reductase; COG: COG0431; Pfam: PF03358; InterPro: IPR005025.
    
  0.742
Your Current Organism:
Anaerococcus lactolyticus
NCBI taxonomy Id: 525254
Other names: A. lactolyticus ATCC 51172, Anaerococcus lactolyticus ATCC 51172, Anaerococcus lactolyticus str. ATCC 51172, Anaerococcus lactolyticus strain ATCC 51172
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