STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (555 aa)    
Predicted Functional Partners:
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
 0.987
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
 
  
 0.966
EEI85237.1
Dinuclear metal center protein, YbgI family; COG: COG0327; Pfam: PF01784; InterPro: IPR002678.
 
   
 0.875
EEI86466.1
RNA polymerase sigma factor SigB; COG: COG0568; Pfam: PF04542,PF04545; InterPro: IPR014284; Belongs to the sigma-70 factor family.
 
  
 0.844
EEI85236.1
Hypothetical protein; COG: COG2384; Pfam: PF04816; InterPro: IPR006901.
       0.822
der
Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
  
 0.818
hydF
Hydrogenase maturation GTPase HydF; Pfam: PF01926; InterPro: IPR005225.
  
  
 0.818
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.816
dnaE
DNA polymerase III, alpha subunit; COG: COG0587; Pfam: PF02811,PF07733,PF01336; InterPro: IPR004805.
 
  
 0.778
trmD
tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
 
  
 0.697
Your Current Organism:
Anaerococcus lactolyticus
NCBI taxonomy Id: 525254
Other names: A. lactolyticus ATCC 51172, Anaerococcus lactolyticus ATCC 51172, Anaerococcus lactolyticus str. ATCC 51172, Anaerococcus lactolyticus strain ATCC 51172
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