| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| eno | fba | HMPREF0072_0436 | HMPREF0072_2170 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Fructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771. | 0.982 |
| eno | fruA | HMPREF0072_0436 | HMPREF0072_1672 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphotransferase system, EIIC; COG: COG1299; Pfam: PF00359,PF02379,PF02378; InterPro: IPR006327. | 0.588 |
| eno | gap | HMPREF0072_0436 | HMPREF0072_0439 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.997 |
| eno | gpmA2 | HMPREF0072_0436 | HMPREF0072_1346 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.987 |
| eno | pfkA | HMPREF0072_0436 | HMPREF0072_0069 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.850 |
| eno | pgi | HMPREF0072_0436 | HMPREF0072_1070 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.990 |
| eno | pgk | HMPREF0072_0436 | HMPREF0072_0438 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoglycerate kinase; COG: COG0126; Pfam: PF00162; InterPro: IPR001576; Belongs to the phosphoglycerate kinase family. | 0.996 |
| eno | pyk | HMPREF0072_0436 | HMPREF0072_0070 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887,PF00391; InterPro: IPR001697; Belongs to the pyruvate kinase family. | 0.998 |
| eno | tkt | HMPREF0072_0436 | HMPREF0072_1556 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Transketolase; COG: COG0021; Pfam: PF00456,PF02779,PF02780; InterPro: IPR005478; Belongs to the transketolase family. | 0.983 |
| eno | tpiA | HMPREF0072_0436 | HMPREF0072_0437 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.999 |
| fba | eno | HMPREF0072_2170 | HMPREF0072_0436 | Fructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.982 |
| fba | fruA | HMPREF0072_2170 | HMPREF0072_1672 | Fructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771. | Phosphotransferase system, EIIC; COG: COG1299; Pfam: PF00359,PF02379,PF02378; InterPro: IPR006327. | 0.972 |
| fba | gap | HMPREF0072_2170 | HMPREF0072_0439 | Fructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.996 |
| fba | gpmA2 | HMPREF0072_2170 | HMPREF0072_1346 | Fructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771. | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.973 |
| fba | pfkA | HMPREF0072_2170 | HMPREF0072_0069 | Fructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.977 |
| fba | pgi | HMPREF0072_2170 | HMPREF0072_1070 | Fructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.984 |
| fba | pgk | HMPREF0072_2170 | HMPREF0072_0438 | Fructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771. | Phosphoglycerate kinase; COG: COG0126; Pfam: PF00162; InterPro: IPR001576; Belongs to the phosphoglycerate kinase family. | 0.986 |
| fba | pyk | HMPREF0072_2170 | HMPREF0072_0070 | Fructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771. | Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887,PF00391; InterPro: IPR001697; Belongs to the pyruvate kinase family. | 0.990 |
| fba | tkt | HMPREF0072_2170 | HMPREF0072_1556 | Fructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771. | Transketolase; COG: COG0021; Pfam: PF00456,PF02779,PF02780; InterPro: IPR005478; Belongs to the transketolase family. | 0.973 |
| fba | tpiA | HMPREF0072_2170 | HMPREF0072_0437 | Fructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.999 |