node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
eda | fbaA | HMPREF0204_13268 | HMPREF0204_10321 | KDPG and KHG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR000887. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.906 |
eda | fsa | HMPREF0204_13268 | HMPREF0204_13427 | KDPG and KHG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR000887. | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.557 |
eda | gapN | HMPREF0204_13268 | HMPREF0204_12820 | KDPG and KHG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR000887. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590. | 0.913 |
eda | glcK | HMPREF0204_13268 | HMPREF0204_10135 | KDPG and KHG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR000887. | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | 0.893 |
eda | glk | HMPREF0204_13268 | HMPREF0204_14737 | KDPG and KHG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR000887. | Glucokinase; Pfam: PF02685; InterPro: IPR003836; Belongs to the bacterial glucokinase family. | 0.939 |
eda | mak | HMPREF0204_13268 | HMPREF0204_10529 | KDPG and KHG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR000887. | ROK family protein; Pfam: PF00480. | 0.702 |
eda | mro | HMPREF0204_13268 | HMPREF0204_13287 | KDPG and KHG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR000887. | Putative galactose mutarotase; Converts alpha-aldose to the beta-anomer. | 0.613 |
eda | pgcA | HMPREF0204_13268 | HMPREF0204_13582 | KDPG and KHG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR000887. | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; COG: COG1109; Pfam: PF02878,PF02879,PF02880; InterPro: IPR016055. | 0.890 |
eda | pgi | HMPREF0204_13268 | HMPREF0204_11097 | KDPG and KHG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR000887. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.919 |
eda | zwf | HMPREF0204_13268 | HMPREF0204_13359 | KDPG and KHG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR000887. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.777 |
fbaA | eda | HMPREF0204_10321 | HMPREF0204_13268 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | KDPG and KHG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR000887. | 0.906 |
fbaA | fsa | HMPREF0204_10321 | HMPREF0204_13427 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.960 |
fbaA | gapN | HMPREF0204_10321 | HMPREF0204_12820 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590. | 0.920 |
fbaA | glcK | HMPREF0204_10321 | HMPREF0204_10135 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | 0.924 |
fbaA | glk | HMPREF0204_10321 | HMPREF0204_14737 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glucokinase; Pfam: PF02685; InterPro: IPR003836; Belongs to the bacterial glucokinase family. | 0.929 |
fbaA | mak | HMPREF0204_10321 | HMPREF0204_10529 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | ROK family protein; Pfam: PF00480. | 0.902 |
fbaA | mro | HMPREF0204_10321 | HMPREF0204_13287 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Putative galactose mutarotase; Converts alpha-aldose to the beta-anomer. | 0.510 |
fbaA | pgcA | HMPREF0204_10321 | HMPREF0204_13582 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; COG: COG1109; Pfam: PF02878,PF02879,PF02880; InterPro: IPR016055. | 0.931 |
fbaA | pgi | HMPREF0204_10321 | HMPREF0204_11097 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.982 |
fbaA | zwf | HMPREF0204_10321 | HMPREF0204_13359 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.769 |