STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glmSGlutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (618 aa)    
Predicted Functional Partners:
purD
Phosphoribosylformylglycinamidine synthase; COG: COG0046; Pfam: PF02844,PF01071,PF02843,PF00586,PF02769; InterPro: IPR010141; Belongs to the GARS family.
    
 0.969
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
 
 0.969
pgi
Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family.
  
 
 0.956
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
    
0.916
glmU
UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
  
 0.913
glnA
Glutamate--ammonia ligase, catalytic domain protein; COG: COG3968; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family.
    
  0.896
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
  
 0.685
nifJ
Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895.
    
  0.659
EFH92326.1
DNA-binding helix-turn-helix protein; COG: COG1396; Pfam: PF01381,PF07883; InterPro: IPR013096.
    
 0.643
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG: COG0138; Pfam: PF02142,PF01808; InterPro: IPR002695.
  
 
 0.632
Your Current Organism:
Finegoldia magna ATCC 53516
NCBI taxonomy Id: 525282
Other names: F. magna ATCC 53516, Finegoldia magna str. ATCC 53516, Finegoldia magna strain ATCC 53516
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