node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEW52925.1 | cinA | HMPREF0494_1902 | HMPREF0494_1148 | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994,PF02464; InterPro: IPR008135; Belongs to the CinA family. | 0.926 |
EEW52925.1 | nadD | HMPREF0494_1902 | HMPREF0494_1903 | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.998 |
EEW52925.1 | nadE | HMPREF0494_1902 | HMPREF0494_2104 | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.568 |
EEW52925.1 | pncB | HMPREF0494_1902 | HMPREF0494_0032 | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.512 |
EEW53411.1 | nadD | HMPREF0494_1346 | HMPREF0494_1903 | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.462 |
EEW53411.1 | pncB | HMPREF0494_1346 | HMPREF0494_0032 | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.490 |
EEW53411.1 | udk | HMPREF0494_1346 | HMPREF0494_1884 | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | Uridine kinase; COG: COG0572; Pfam: PF00485; InterPro: IPR000764. | 0.455 |
EEW53446.1 | nadD | HMPREF0494_1381 | HMPREF0494_1903 | Hypothetical protein. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.421 |
EEW53446.1 | pncB | HMPREF0494_1381 | HMPREF0494_0032 | Hypothetical protein. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.490 |
EEW53446.1 | udk | HMPREF0494_1381 | HMPREF0494_1884 | Hypothetical protein. | Uridine kinase; COG: COG0572; Pfam: PF00485; InterPro: IPR000764. | 0.429 |
EEW54774.1 | cinA | HMPREF0494_0031 | HMPREF0494_1148 | Hydrolase, NUDIX family; COG: COG1051; Pfam: PF00293. | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994,PF02464; InterPro: IPR008135; Belongs to the CinA family. | 0.861 |
EEW54774.1 | nadD | HMPREF0494_0031 | HMPREF0494_1903 | Hydrolase, NUDIX family; COG: COG1051; Pfam: PF00293. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.644 |
EEW54774.1 | nadE | HMPREF0494_0031 | HMPREF0494_2104 | Hydrolase, NUDIX family; COG: COG1051; Pfam: PF00293. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.663 |
EEW54774.1 | pncA2 | HMPREF0494_0031 | HMPREF0494_0033 | Hydrolase, NUDIX family; COG: COG1051; Pfam: PF00293. | Isochorismatase family protein; COG: COG1335; Pfam: PF00857; InterPro: IPR000868. | 0.575 |
EEW54774.1 | pncB | HMPREF0494_0031 | HMPREF0494_0032 | Hydrolase, NUDIX family; COG: COG1051; Pfam: PF00293. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.754 |
cinA | EEW52925.1 | HMPREF0494_1148 | HMPREF0494_1902 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994,PF02464; InterPro: IPR008135; Belongs to the CinA family. | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | 0.926 |
cinA | EEW54774.1 | HMPREF0494_1148 | HMPREF0494_0031 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994,PF02464; InterPro: IPR008135; Belongs to the CinA family. | Hydrolase, NUDIX family; COG: COG1051; Pfam: PF00293. | 0.861 |
cinA | nadD | HMPREF0494_1148 | HMPREF0494_1903 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994,PF02464; InterPro: IPR008135; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.985 |
cinA | nadE | HMPREF0494_1148 | HMPREF0494_2104 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994,PF02464; InterPro: IPR008135; Belongs to the CinA family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.883 |
cinA | pncB | HMPREF0494_1148 | HMPREF0494_0032 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994,PF02464; InterPro: IPR008135; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.935 |