node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEW54706.1 | deoD | HMPREF0494_0182 | HMPREF0494_0320 | Transcriptional regulator, Sir2 family; COG: COG0846; Pfam: PF02146; InterPro: IPR003000. | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | 0.942 |
EEW54706.1 | pncA2 | HMPREF0494_0182 | HMPREF0494_0033 | Transcriptional regulator, Sir2 family; COG: COG0846; Pfam: PF02146; InterPro: IPR003000. | Isochorismatase family protein; COG: COG1335; Pfam: PF00857; InterPro: IPR000868. | 0.478 |
EEW54706.1 | pncB | HMPREF0494_0182 | HMPREF0494_0032 | Transcriptional regulator, Sir2 family; COG: COG0846; Pfam: PF02146; InterPro: IPR003000. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.449 |
EEW54774.1 | guaA-2 | HMPREF0494_0031 | HMPREF0494_0690 | Hydrolase, NUDIX family; COG: COG1051; Pfam: PF00293. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.527 |
EEW54774.1 | pncA2 | HMPREF0494_0031 | HMPREF0494_0033 | Hydrolase, NUDIX family; COG: COG1051; Pfam: PF00293. | Isochorismatase family protein; COG: COG1335; Pfam: PF00857; InterPro: IPR000868. | 0.575 |
EEW54774.1 | pncB | HMPREF0494_0031 | HMPREF0494_0032 | Hydrolase, NUDIX family; COG: COG1051; Pfam: PF00293. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.754 |
EEW54777.1 | pncA2 | HMPREF0494_0034 | HMPREF0494_0033 | Hypothetical protein. | Isochorismatase family protein; COG: COG1335; Pfam: PF00857; InterPro: IPR000868. | 0.427 |
EEW54777.1 | pncB | HMPREF0494_0034 | HMPREF0494_0032 | Hypothetical protein. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.427 |
deoD | EEW54706.1 | HMPREF0494_0320 | HMPREF0494_0182 | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | Transcriptional regulator, Sir2 family; COG: COG0846; Pfam: PF02146; InterPro: IPR003000. | 0.942 |
deoD | pncA2 | HMPREF0494_0320 | HMPREF0494_0033 | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | Isochorismatase family protein; COG: COG1335; Pfam: PF00857; InterPro: IPR000868. | 0.414 |
deoD | pncB | HMPREF0494_0320 | HMPREF0494_0032 | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.832 |
gpsA | pncA2 | HMPREF0494_1025 | HMPREF0494_0033 | Glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Pfam: PF01210,PF07479; InterPro: IPR006168; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Isochorismatase family protein; COG: COG1335; Pfam: PF00857; InterPro: IPR000868. | 0.457 |
guaA-2 | EEW54774.1 | HMPREF0494_0690 | HMPREF0494_0031 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Hydrolase, NUDIX family; COG: COG1051; Pfam: PF00293. | 0.527 |
guaA-2 | pncA2 | HMPREF0494_0690 | HMPREF0494_0033 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Isochorismatase family protein; COG: COG1335; Pfam: PF00857; InterPro: IPR000868. | 0.408 |
pncA2 | EEW54706.1 | HMPREF0494_0033 | HMPREF0494_0182 | Isochorismatase family protein; COG: COG1335; Pfam: PF00857; InterPro: IPR000868. | Transcriptional regulator, Sir2 family; COG: COG0846; Pfam: PF02146; InterPro: IPR003000. | 0.478 |
pncA2 | EEW54774.1 | HMPREF0494_0033 | HMPREF0494_0031 | Isochorismatase family protein; COG: COG1335; Pfam: PF00857; InterPro: IPR000868. | Hydrolase, NUDIX family; COG: COG1051; Pfam: PF00293. | 0.575 |
pncA2 | EEW54777.1 | HMPREF0494_0033 | HMPREF0494_0034 | Isochorismatase family protein; COG: COG1335; Pfam: PF00857; InterPro: IPR000868. | Hypothetical protein. | 0.427 |
pncA2 | deoD | HMPREF0494_0033 | HMPREF0494_0320 | Isochorismatase family protein; COG: COG1335; Pfam: PF00857; InterPro: IPR000868. | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | 0.414 |
pncA2 | gpsA | HMPREF0494_0033 | HMPREF0494_1025 | Isochorismatase family protein; COG: COG1335; Pfam: PF00857; InterPro: IPR000868. | Glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Pfam: PF01210,PF07479; InterPro: IPR006168; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.457 |
pncA2 | guaA-2 | HMPREF0494_0033 | HMPREF0494_0690 | Isochorismatase family protein; COG: COG1335; Pfam: PF00857; InterPro: IPR000868. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.408 |