STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvaAhydroxymethylglutaryl-CoA reductase, degradative; COG: COG1257; InterPro: IPR004553; Belongs to the HMG-CoA reductase family. (418 aa)    
Predicted Functional Partners:
mvaS
hydroxymethylglutaryl-CoA synthase; COG: COG3425; Pfam: PF01154,PF08540; InterPro: IPR011554.
 
 0.999
mvk
Mevalonate kinase; COG: COG1577; Pfam: PF00288,PF08544; InterPro: IPR006205.
 0.999
mvaD
Diphosphomevalonate decarboxylase; COG: COG3407; Pfam: PF00288,PF08544; InterPro: IPR005935.
 
 
 0.961
atoB
acetyl-CoA C-acetyltransferase; COG: COG0183; Pfam: PF00108,PF02803; InterPro: IPR002155; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.955
EEW54706.1
Transcriptional regulator, Sir2 family; COG: COG0846; Pfam: PF02146; InterPro: IPR003000.
  
  
 0.863
EEW54705.1
Hypothetical protein.
  
    0.858
mvaK
Phosphomevalonate kinase; COG: COG1577; Pfam: PF00288,PF08544; InterPro: IPR005917.
 
 0.855
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
   
 0.822
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; COG: COG1575; Pfam: PF01040.
   
 
 0.801
ppx2
Putative exopolyphosphatase; COG: COG0248; Pfam: PF02541; InterPro: IPR003695.
       0.795
Your Current Organism:
Lactobacillus antri
NCBI taxonomy Id: 525309
Other names: L. antri DSM 16041, Lactobacillus antri DSM 16041, Lactobacillus antri str. DSM 16041, Lactobacillus antri strain DSM 16041
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.