node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEW53539.1 | EEW54083.1 | HMPREF0494_1275 | HMPREF0494_0741 | Hypothetical protein; 3.1.3.16. | Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.617 |
EEW53539.1 | EEW54412.1 | HMPREF0494_1275 | HMPREF0494_0400 | Hypothetical protein; 3.1.3.16. | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | 0.438 |
EEW53539.1 | dnaJ | HMPREF0494_1275 | HMPREF0494_1432 | Hypothetical protein; 3.1.3.16. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.668 |
EEW53539.1 | glpF | HMPREF0494_1275 | HMPREF0494_1441 | Hypothetical protein; 3.1.3.16. | MIP family channel protein; COG: COG0580; Pfam: PF00230; InterPro: IPR000425; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.679 |
EEW53539.1 | ndk | HMPREF0494_1275 | HMPREF0494_0151 | Hypothetical protein; 3.1.3.16. | Nucleoside diphosphate kinase; COG: COG0105; Pfam: PF00334; InterPro: IPR001564; Belongs to the NDK family. | 0.708 |
EEW54083.1 | EEW53539.1 | HMPREF0494_0741 | HMPREF0494_1275 | Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Hypothetical protein; 3.1.3.16. | 0.617 |
EEW54083.1 | EEW54412.1 | HMPREF0494_0741 | HMPREF0494_0400 | Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | 0.549 |
EEW54083.1 | dnaJ | HMPREF0494_0741 | HMPREF0494_1432 | Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.992 |
EEW54083.1 | glpF | HMPREF0494_0741 | HMPREF0494_1441 | Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | MIP family channel protein; COG: COG0580; Pfam: PF00230; InterPro: IPR000425; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.658 |
EEW54083.1 | menE | HMPREF0494_0741 | HMPREF0494_0669 | Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | O-succinylbenzoate-CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily. | 0.843 |
EEW54083.1 | ndk | HMPREF0494_0741 | HMPREF0494_0151 | Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Nucleoside diphosphate kinase; COG: COG0105; Pfam: PF00334; InterPro: IPR001564; Belongs to the NDK family. | 0.788 |
EEW54083.1 | stp | HMPREF0494_0741 | HMPREF0494_1838 | Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Stage II sporulation protein E; COG: COG0631; Pfam: PF07228; InterPro: IPR001932. | 0.617 |
EEW54411.1 | EEW54412.1 | HMPREF0494_0399 | HMPREF0494_0400 | Oxidoreductase, aldo/keto reductase family protein; COG: COG4989; Pfam: PF00248; InterPro: IPR001395. | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | 0.759 |
EEW54411.1 | EEW54413.1 | HMPREF0494_0399 | HMPREF0494_0401 | Oxidoreductase, aldo/keto reductase family protein; COG: COG4989; Pfam: PF00248; InterPro: IPR001395. | Transcriptional regulator, MerR family; Pfam: PF00376,PF09278; InterPro: IPR000551. | 0.478 |
EEW54411.1 | hxlR | HMPREF0494_0399 | HMPREF0494_0398 | Oxidoreductase, aldo/keto reductase family protein; COG: COG4989; Pfam: PF00248; InterPro: IPR001395. | Transcriptional regulator, HxlR family; COG: COG1733; Pfam: PF01638; InterPro: IPR002577. | 0.527 |
EEW54412.1 | EEW53539.1 | HMPREF0494_0400 | HMPREF0494_1275 | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | Hypothetical protein; 3.1.3.16. | 0.438 |
EEW54412.1 | EEW54083.1 | HMPREF0494_0400 | HMPREF0494_0741 | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.549 |
EEW54412.1 | EEW54411.1 | HMPREF0494_0400 | HMPREF0494_0399 | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | Oxidoreductase, aldo/keto reductase family protein; COG: COG4989; Pfam: PF00248; InterPro: IPR001395. | 0.759 |
EEW54412.1 | EEW54413.1 | HMPREF0494_0400 | HMPREF0494_0401 | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | Transcriptional regulator, MerR family; Pfam: PF00376,PF09278; InterPro: IPR000551. | 0.507 |
EEW54412.1 | dnaJ | HMPREF0494_0400 | HMPREF0494_1432 | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.514 |