STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldh2L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (311 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697; Belongs to the pyruvate kinase family.
  
 0.916
acoB
Transketolase, C-terminal domain protein; COG: COG0022; Pfam: PF02779,PF02780; InterPro: IPR005475.
   
 0.875
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.856
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 
 0.852
hicD5
L-2-hydroxyisocaproate dehydrogenase; COG: COG0039; Pfam: PF00056,PF02866; InterPro: IPR001236; Belongs to the LDH/MDH superfamily.
  
  
 
0.851
zwf
Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
   
 
 0.851
xfp
D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; COG: COG3957; Pfam: PF03894; InterPro: IPR005593.
    
 0.849
fba
Fructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771.
   
 
 0.844
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.833
frdA
COG: COG1053; Pfam: PF00890; InterPro: IPR010960; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 0.833
Your Current Organism:
Lactobacillus antri
NCBI taxonomy Id: 525309
Other names: L. antri DSM 16041, Lactobacillus antri DSM 16041, Lactobacillus antri str. DSM 16041, Lactobacillus antri strain DSM 16041
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