STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmeMalic enzyme, NAD binding domain protein; COG: COG0281; Pfam: PF00390,PF03949; InterPro: IPR016040. (386 aa)    
Predicted Functional Partners:
pta
Phosphate acetyltransferase; COG: COG0280; Pfam: PF01515; InterPro: IPR002505.
 
 
 0.949
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.894
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.884
citE
Citrate (pro-3S)-lyase, beta subunit; COG: COG2301; Pfam: PF03328; InterPro: IPR006475; overlaps another CDS with the same product name; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.866
acoB
Transketolase, C-terminal domain protein; COG: COG0022; Pfam: PF02779,PF02780; InterPro: IPR005475.
  
 
 0.863
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.851
ppsA
Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
  
 
 0.850
hicD5
L-2-hydroxyisocaproate dehydrogenase; COG: COG0039; Pfam: PF00056,PF02866; InterPro: IPR001236; Belongs to the LDH/MDH superfamily.
  
 0.835
citD
Citrate lyase acyl carrier protein; Covalent carrier of the coenzyme of citrate lyase.
  
    0.829
citC
[citrate (pro-3S)-lyase] ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.
  
    0.812
Your Current Organism:
Lactobacillus antri
NCBI taxonomy Id: 525309
Other names: L. antri DSM 16041, Lactobacillus antri DSM 16041, Lactobacillus antri str. DSM 16041, Lactobacillus antri strain DSM 16041
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.