STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEW54106.1Transporter, major facilitator family protein; COG: COG0477; Pfam: PF07690; InterPro: IPR011701. (472 aa)    
Predicted Functional Partners:
nrdE
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
   
  0.442
asd
Aspartate-semialdehyde dehydrogenase; COG: COG0136; Pfam: PF01118,PF02774; InterPro: IPR005676; Belongs to the aspartate-semialdehyde dehydrogenase family.
    
  0.433
nrdF
Ribonucleoside-diphosphate reductase, beta subunit; COG: COG0208; Pfam: PF00268; InterPro: IPR000358.
   
 
  0.430
narG
Nitrate reductase, alpha subunit; COG: COG5013; Pfam: PF00384,PF01568; InterPro: IPR006468; overlaps another CDS with the same product name; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
 0.430
gadB
Glutamate decarboxylase; COG: COG0076; Pfam: PF00282; InterPro: IPR010107; Belongs to the group II decarboxylase family.
   
 
  0.429
tdk
Thymidine kinase; COG: COG1435; Pfam: PF00265; InterPro: IPR001267.
     
 0.420
ndk
Nucleoside diphosphate kinase; COG: COG0105; Pfam: PF00334; InterPro: IPR001564; Belongs to the NDK family.
   
 
  0.416
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
 
  0.416
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
  0.414
EEW54105.1
uracil-DNA glycosylase, family 4; COG: COG1573; Pfam: PF03167; InterPro: IPR005122.
       0.408
Your Current Organism:
Lactobacillus antri
NCBI taxonomy Id: 525309
Other names: L. antri DSM 16041, Lactobacillus antri DSM 16041, Lactobacillus antri str. DSM 16041, Lactobacillus antri strain DSM 16041
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