node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEW54303.1 | efp | HMPREF0494_0486 | HMPREF0494_0709 | Hypothetical protein; COG: COG0702; Pfam: PF01370; InterPro: IPR016040. | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.763 |
EEW54303.1 | rpsF | HMPREF0494_0486 | HMPREF0494_0420 | Hypothetical protein; COG: COG0702; Pfam: PF01370; InterPro: IPR016040. | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.779 |
EEW54303.1 | rpsG | HMPREF0494_0486 | HMPREF0494_0823 | Hypothetical protein; COG: COG0702; Pfam: PF01370; InterPro: IPR016040. | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.999 |
EEW54303.1 | rpsJ | HMPREF0494_0486 | HMPREF0494_0826 | Hypothetical protein; COG: COG0702; Pfam: PF01370; InterPro: IPR016040. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.999 |
EEW54303.1 | rpsL | HMPREF0494_0486 | HMPREF0494_0822 | Hypothetical protein; COG: COG0702; Pfam: PF01370; InterPro: IPR016040. | Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.999 |
EEW54303.1 | selB | HMPREF0494_0486 | HMPREF0494_0240 | Hypothetical protein; COG: COG0702; Pfam: PF01370; InterPro: IPR016040. | Selenocysteine-specific translation elongation factor; COG: COG3276; Pfam: PF00009,PF03144,PF09107; InterPro: IPR004535. | 0.775 |
efp | EEW54303.1 | HMPREF0494_0709 | HMPREF0494_0486 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Hypothetical protein; COG: COG0702; Pfam: PF01370; InterPro: IPR016040. | 0.763 |
efp | rplI | HMPREF0494_0709 | HMPREF0494_0416 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Ribosomal protein L9; Binds to the 23S rRNA. | 0.990 |
efp | rpmE | HMPREF0494_0709 | HMPREF0494_0220 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Ribosomal protein L31; COG: COG0254; Pfam: PF01197; InterPro: IPR002150. | 0.987 |
efp | rpmH | HMPREF0494_0709 | HMPREF0494_0427 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Ribosomal protein L34; COG: COG0230; Pfam: PF00468; InterPro: IPR000271; Belongs to the bacterial ribosomal protein bL34 family. | 0.967 |
efp | rpsF | HMPREF0494_0709 | HMPREF0494_0420 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.990 |
efp | rpsG | HMPREF0494_0709 | HMPREF0494_0823 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.999 |
efp | rpsJ | HMPREF0494_0709 | HMPREF0494_0826 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.999 |
efp | rpsL | HMPREF0494_0709 | HMPREF0494_0822 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.999 |
efp | rpsR | HMPREF0494_0709 | HMPREF0494_0418 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.988 |
efp | selB | HMPREF0494_0709 | HMPREF0494_0240 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Selenocysteine-specific translation elongation factor; COG: COG3276; Pfam: PF00009,PF03144,PF09107; InterPro: IPR004535. | 0.657 |
rplI | efp | HMPREF0494_0416 | HMPREF0494_0709 | Ribosomal protein L9; Binds to the 23S rRNA. | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.990 |
rplI | rpmE | HMPREF0494_0416 | HMPREF0494_0220 | Ribosomal protein L9; Binds to the 23S rRNA. | Ribosomal protein L31; COG: COG0254; Pfam: PF01197; InterPro: IPR002150. | 0.999 |
rplI | rpmH | HMPREF0494_0416 | HMPREF0494_0427 | Ribosomal protein L9; Binds to the 23S rRNA. | Ribosomal protein L34; COG: COG0230; Pfam: PF00468; InterPro: IPR000271; Belongs to the bacterial ribosomal protein bL34 family. | 0.999 |
rplI | rpsF | HMPREF0494_0416 | HMPREF0494_0420 | Ribosomal protein L9; Binds to the 23S rRNA. | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.999 |