node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEW52768.1 | EEW53411.1 | HMPREF0494_2053 | HMPREF0494_1346 | Hypothetical protein. | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | 0.830 |
EEW52768.1 | dnaJ | HMPREF0494_2053 | HMPREF0494_1432 | Hypothetical protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.972 |
EEW52768.1 | rpoA | HMPREF0494_2053 | HMPREF0494_0852 | Hypothetical protein. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.549 |
EEW52768.1 | rpoB | HMPREF0494_2053 | HMPREF0494_0818 | Hypothetical protein. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.405 |
EEW53411.1 | EEW52768.1 | HMPREF0494_1346 | HMPREF0494_2053 | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | Hypothetical protein. | 0.830 |
EEW53411.1 | alaS | HMPREF0494_1346 | HMPREF0494_1160 | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.905 |
EEW53411.1 | dnaJ | HMPREF0494_1346 | HMPREF0494_1432 | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.824 |
EEW53411.1 | dnaK | HMPREF0494_1346 | HMPREF0494_1431 | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.830 |
EEW53411.1 | pgm | HMPREF0494_1346 | HMPREF0494_1345 | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | Phosphoglycerate mutase family protein; COG: COG0406; Pfam: PF00300; InterPro: IPR013078. | 0.884 |
EEW53411.1 | recD | HMPREF0494_1346 | HMPREF0494_1347 | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.910 |
EEW53411.1 | ribA | HMPREF0494_1346 | HMPREF0494_0462 | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.868 |
EEW53411.1 | ribB | HMPREF0494_1346 | HMPREF0494_0494 | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.868 |
EEW53411.1 | rpoA | HMPREF0494_1346 | HMPREF0494_0852 | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.860 |
EEW53411.1 | rpoB | HMPREF0494_1346 | HMPREF0494_0818 | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.836 |
alaS | EEW53411.1 | HMPREF0494_1160 | HMPREF0494_1346 | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | 0.905 |
alaS | rpoB | HMPREF0494_1160 | HMPREF0494_0818 | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.431 |
dnaJ | EEW52768.1 | HMPREF0494_1432 | HMPREF0494_2053 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Hypothetical protein. | 0.972 |
dnaJ | EEW53411.1 | HMPREF0494_1432 | HMPREF0494_1346 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Tetratricopeptide repeat protein; Pfam: PF00515,PF07719; InterPro: IPR011990. | 0.824 |
dnaJ | dnaK | HMPREF0494_1432 | HMPREF0494_1431 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
dnaJ | ribA | HMPREF0494_1432 | HMPREF0494_0462 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.451 |