STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acoBTransketolase, C-terminal domain protein; COG: COG0022; Pfam: PF02779,PF02780; InterPro: IPR005475. (325 aa)    
Predicted Functional Partners:
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
pdhC
2-oxo acid dehydrogenase acyltransferase (catalytic domain); COG: COG0508; Pfam: PF00364,PF02817,PF00198; InterPro: IPR001078.
 0.999
lpdA
Dihydrolipoyl dehydrogenase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006258.
 0.995
ykgC
Pyridine nucleotide-disulfide oxidoreductase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR013027.
 0.970
EEW52692.1
Pyridine nucleotide-disulfide oxidoreductase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR013027.
 0.970
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.949
nemA
Pyridine nucleotide-disulfide oxidoreductase; COG: COG1902; Pfam: PF00724,PF07992,PF00070; InterPro: IPR013785.
  
 0.947
fba
Fructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771.
  
 
 0.946
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.944
pyk
Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697; Belongs to the pyruvate kinase family.
  
 
 0.944
Your Current Organism:
Lactobacillus antri
NCBI taxonomy Id: 525309
Other names: L. antri DSM 16041, Lactobacillus antri DSM 16041, Lactobacillus antri str. DSM 16041, Lactobacillus antri strain DSM 16041
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.