STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
holADNA polymerase III, delta subunit; COG: COG1466; Pfam: PF06144; InterPro: IPR005790. (340 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.999
dnaE
DNA polymerase III, alpha subunit; COG: COG0587; Pfam: PF02811,PF07733,PF01336; InterPro: IPR004805.
  
 0.999
holB
DNA polymerase III, delta' subunit; COG: COG0470; InterPro: IPR004622.
 
 
 0.993
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.991
dnaQ
Exonuclease; COG: COG0847; Pfam: PF00929; InterPro: IPR006055.
    
 0.975
dinG
Putative DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease.
    
 0.943
polC
DNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
 0.941
comEC
DNA internalization competence protein ComEC/Rec2-like protein; COG: COG2333; Pfam: PF03772,PF00753; InterPro: IPR004797.
 
   
 0.938
EEW53948.1
Putative DNA polymerase III, epsilon subunit; Pfam: PF00929; InterPro: IPR006055.
    
 0.937
comEB
ComE operon protein 2; COG: COG2131; Pfam: PF00383; InterPro: IPR013404.
  
    0.837
Your Current Organism:
Lactobacillus antri
NCBI taxonomy Id: 525309
Other names: L. antri DSM 16041, Lactobacillus antri DSM 16041, Lactobacillus antri str. DSM 16041, Lactobacillus antri strain DSM 16041
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.