node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEW54159.1 | EEW54466.1 | HMPREF0494_0658 | HMPREF0494_0354 | Hydrolase, NUDIX family; Pfam: PF00293; InterPro: IPR000086. | RelA/SpoT domain protein; COG: COG2357; Pfam: PF04607; InterPro: IPR007685. | 0.925 |
EEW54159.1 | moaA | HMPREF0494_0658 | HMPREF0494_1521 | Hydrolase, NUDIX family; Pfam: PF00293; InterPro: IPR000086. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | 0.894 |
EEW54159.1 | ndk | HMPREF0494_0658 | HMPREF0494_0151 | Hydrolase, NUDIX family; Pfam: PF00293; InterPro: IPR000086. | Nucleoside diphosphate kinase; COG: COG0105; Pfam: PF00334; InterPro: IPR001564; Belongs to the NDK family. | 0.927 |
EEW54159.1 | nrdD | HMPREF0494_0658 | HMPREF0494_1095 | Hydrolase, NUDIX family; Pfam: PF00293; InterPro: IPR000086. | Anaerobic ribonucleoside-triphosphate reductase; COG: COG1328; Pfam: PF01228; InterPro: IPR012833. | 0.925 |
EEW54159.1 | relA | HMPREF0494_0658 | HMPREF0494_1308 | Hydrolase, NUDIX family; Pfam: PF00293; InterPro: IPR000086. | RelA/SpoT domain protein; COG: COG2357; Pfam: PF04607; InterPro: IPR007685. | 0.925 |
EEW54159.1 | relA2 | HMPREF0494_0658 | HMPREF0494_1460 | Hydrolase, NUDIX family; Pfam: PF00293; InterPro: IPR000086. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.925 |
EEW54466.1 | EEW54159.1 | HMPREF0494_0354 | HMPREF0494_0658 | RelA/SpoT domain protein; COG: COG2357; Pfam: PF04607; InterPro: IPR007685. | Hydrolase, NUDIX family; Pfam: PF00293; InterPro: IPR000086. | 0.925 |
EEW54466.1 | moaA | HMPREF0494_0354 | HMPREF0494_1521 | RelA/SpoT domain protein; COG: COG2357; Pfam: PF04607; InterPro: IPR007685. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | 0.924 |
EEW54466.1 | ndk | HMPREF0494_0354 | HMPREF0494_0151 | RelA/SpoT domain protein; COG: COG2357; Pfam: PF04607; InterPro: IPR007685. | Nucleoside diphosphate kinase; COG: COG0105; Pfam: PF00334; InterPro: IPR001564; Belongs to the NDK family. | 0.960 |
EEW54466.1 | relA | HMPREF0494_0354 | HMPREF0494_1308 | RelA/SpoT domain protein; COG: COG2357; Pfam: PF04607; InterPro: IPR007685. | RelA/SpoT domain protein; COG: COG2357; Pfam: PF04607; InterPro: IPR007685. | 0.937 |
EEW54466.1 | relA2 | HMPREF0494_0354 | HMPREF0494_1460 | RelA/SpoT domain protein; COG: COG2357; Pfam: PF04607; InterPro: IPR007685. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.967 |
moaA | EEW54159.1 | HMPREF0494_1521 | HMPREF0494_0658 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | Hydrolase, NUDIX family; Pfam: PF00293; InterPro: IPR000086. | 0.894 |
moaA | EEW54466.1 | HMPREF0494_1521 | HMPREF0494_0354 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | RelA/SpoT domain protein; COG: COG2357; Pfam: PF04607; InterPro: IPR007685. | 0.924 |
moaA | moaC | HMPREF0494_1521 | HMPREF0494_1523 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.999 |
moaA | moeA | HMPREF0494_1521 | HMPREF0494_1237 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | Prevent-host-death family protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.886 |
moaA | ndk | HMPREF0494_1521 | HMPREF0494_0151 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | Nucleoside diphosphate kinase; COG: COG0105; Pfam: PF00334; InterPro: IPR001564; Belongs to the NDK family. | 0.906 |
moaA | nrdD | HMPREF0494_1521 | HMPREF0494_1095 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | Anaerobic ribonucleoside-triphosphate reductase; COG: COG1328; Pfam: PF01228; InterPro: IPR012833. | 0.911 |
moaA | relA | HMPREF0494_1521 | HMPREF0494_1308 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | RelA/SpoT domain protein; COG: COG2357; Pfam: PF04607; InterPro: IPR007685. | 0.924 |
moaA | relA2 | HMPREF0494_1521 | HMPREF0494_1460 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.928 |
moaA | ribA | HMPREF0494_1521 | HMPREF0494_0462 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.929 |