node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEW53114.1 | coaBC | HMPREF0494_1837 | HMPREF0494_1842 | Kinase domain protein; COG: COG0515; Pfam: PF00069,PF03793; InterPro: IPR002290. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.761 |
EEW53114.1 | fmt | HMPREF0494_1837 | HMPREF0494_1840 | Kinase domain protein; COG: COG0515; Pfam: PF00069,PF03793; InterPro: IPR002290. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.837 |
EEW53114.1 | gmk | HMPREF0494_1837 | HMPREF0494_1844 | Kinase domain protein; COG: COG0515; Pfam: PF00069,PF03793; InterPro: IPR002290. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.673 |
EEW53114.1 | priA | HMPREF0494_1837 | HMPREF0494_1841 | Kinase domain protein; COG: COG0515; Pfam: PF00069,PF03793; InterPro: IPR002290. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.755 |
EEW53114.1 | rpe | HMPREF0494_1837 | HMPREF0494_1835 | Kinase domain protein; COG: COG0515; Pfam: PF00069,PF03793; InterPro: IPR002290. | Ribulose-phosphate 3-epimerase; COG: COG0036; Pfam: PF00834; InterPro: IPR013785; Belongs to the ribulose-phosphate 3-epimerase family. | 0.897 |
EEW53114.1 | rsgA | HMPREF0494_1837 | HMPREF0494_1836 | Kinase domain protein; COG: COG0515; Pfam: PF00069,PF03793; InterPro: IPR002290. | Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | 0.953 |
EEW53114.1 | stp | HMPREF0494_1837 | HMPREF0494_1838 | Kinase domain protein; COG: COG0515; Pfam: PF00069,PF03793; InterPro: IPR002290. | Stage II sporulation protein E; COG: COG0631; Pfam: PF07228; InterPro: IPR001932. | 0.999 |
EEW53114.1 | sun | HMPREF0494_1837 | HMPREF0494_1839 | Kinase domain protein; COG: COG0515; Pfam: PF00069,PF03793; InterPro: IPR002290. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.880 |
coaBC | EEW53114.1 | HMPREF0494_1842 | HMPREF0494_1837 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Kinase domain protein; COG: COG0515; Pfam: PF00069,PF03793; InterPro: IPR002290. | 0.761 |
coaBC | fmt | HMPREF0494_1842 | HMPREF0494_1840 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.806 |
coaBC | gmk | HMPREF0494_1842 | HMPREF0494_1844 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.713 |
coaBC | priA | HMPREF0494_1842 | HMPREF0494_1841 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.944 |
coaBC | rpe | HMPREF0494_1842 | HMPREF0494_1835 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Ribulose-phosphate 3-epimerase; COG: COG0036; Pfam: PF00834; InterPro: IPR013785; Belongs to the ribulose-phosphate 3-epimerase family. | 0.775 |
coaBC | rsgA | HMPREF0494_1842 | HMPREF0494_1836 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | 0.733 |
coaBC | stp | HMPREF0494_1842 | HMPREF0494_1838 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Stage II sporulation protein E; COG: COG0631; Pfam: PF07228; InterPro: IPR001932. | 0.785 |
coaBC | sun | HMPREF0494_1842 | HMPREF0494_1839 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.828 |
fmt | EEW53114.1 | HMPREF0494_1840 | HMPREF0494_1837 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Kinase domain protein; COG: COG0515; Pfam: PF00069,PF03793; InterPro: IPR002290. | 0.837 |
fmt | coaBC | HMPREF0494_1840 | HMPREF0494_1842 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.806 |
fmt | gmk | HMPREF0494_1840 | HMPREF0494_1844 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.715 |
fmt | priA | HMPREF0494_1840 | HMPREF0494_1841 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.969 |