node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEW52921.1 | EEW52923.1 | HMPREF0494_1898 | HMPREF0494_1900 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | 0.744 |
EEW52921.1 | EEW52925.1 | HMPREF0494_1898 | HMPREF0494_1902 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | 0.711 |
EEW52921.1 | EEW52927.1 | HMPREF0494_1898 | HMPREF0494_1904 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | RNA-binding protein, YhbY family; COG: COG1534; Pfam: PF01985; InterPro: IPR001890. | 0.700 |
EEW52921.1 | nadD | HMPREF0494_1898 | HMPREF0494_1903 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.708 |
EEW52921.1 | rplT | HMPREF0494_1898 | HMPREF0494_1907 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.818 |
EEW52921.1 | rsfS | HMPREF0494_1898 | HMPREF0494_1901 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.705 |
EEW52921.1 | tmcAL | HMPREF0494_1898 | HMPREF0494_1899 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. | 0.745 |
EEW52921.1 | yqeG | HMPREF0494_1898 | HMPREF0494_1906 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | HAD phosphatase, family IIIA; COG: COG2179; Pfam: PF00702; InterPro: IPR010021. | 0.681 |
EEW52921.1 | yqeH | HMPREF0494_1898 | HMPREF0494_1905 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | Ribosome biogenesis GTPase YqeH; COG: COG1161; Pfam: PF01926; InterPro: IPR002917. | 0.821 |
EEW52923.1 | EEW52921.1 | HMPREF0494_1900 | HMPREF0494_1898 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | 0.744 |
EEW52923.1 | EEW52925.1 | HMPREF0494_1900 | HMPREF0494_1902 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | 0.910 |
EEW52923.1 | EEW52927.1 | HMPREF0494_1900 | HMPREF0494_1904 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | RNA-binding protein, YhbY family; COG: COG1534; Pfam: PF01985; InterPro: IPR001890. | 0.897 |
EEW52923.1 | mtnN | HMPREF0494_1900 | HMPREF0494_1341 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.463 |
EEW52923.1 | nadD | HMPREF0494_1900 | HMPREF0494_1903 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.872 |
EEW52923.1 | rplT | HMPREF0494_1900 | HMPREF0494_1907 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.479 |
EEW52923.1 | rsfS | HMPREF0494_1900 | HMPREF0494_1901 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.954 |
EEW52923.1 | tmcAL | HMPREF0494_1900 | HMPREF0494_1899 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. | 0.853 |
EEW52923.1 | yqeG | HMPREF0494_1900 | HMPREF0494_1906 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | HAD phosphatase, family IIIA; COG: COG2179; Pfam: PF00702; InterPro: IPR010021. | 0.832 |
EEW52923.1 | yqeH | HMPREF0494_1900 | HMPREF0494_1905 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | Ribosome biogenesis GTPase YqeH; COG: COG1161; Pfam: PF01926; InterPro: IPR002917. | 0.849 |
EEW52925.1 | EEW52921.1 | HMPREF0494_1902 | HMPREF0494_1898 | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | 0.711 |