Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
thiMPutative hydroxyethylthiazole kinase; COG: COG2145; Pfam: PF02110; InterPro: IPR000417. (262 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate diphosphorylase; COG: COG0352; Pfam: PF02581; InterPro: IPR013785.
 
 0.999
thiE-2
Thiamine-phosphate diphosphorylase; COG: COG0352; Pfam: PF02581; InterPro: IPR013785.
 
 0.999
thiD
Phosphomethylpyrimidine kinase; COG: COG0351; Pfam: PF08543; InterPro: IPR004399.
 
 0.993
EEI20403.1
TENA/THI-4 family protein; COG: COG0819; Pfam: PF03070; InterPro: IPR016084.
 
  
 0.973
EEI20533.1
TENA/THI-4 family protein; COG: COG0819; Pfam: PF03070; InterPro: IPR016084.
 
  
 0.972
thiD-2
Phosphomethylpyrimidine kinase; COG: COG0351; Pfam: PF08543; InterPro: IPR004399.
 
 0.965
nudF
Hydrolase, NUDIX family; COG: COG0494; Pfam: PF00293; InterPro: IPR000086.
     
  0.863
EEI20713.1
Hydrolase, NUDIX family; COG: COG0494; Pfam: PF00293; InterPro: IPR000086.
     
  0.849
EEI20023.1
Mutator mutT protein; COG: COG0494; Pfam: PF00293; InterPro: IPR000086.
     
  0.813
thiS
Thiamine biosynthesis protein ThiS; Pfam: PF02597; InterPro: IPR012675.
  
 
  0.795
Your Current Organism:
Lactobacillus buchneri ATCC 11577
NCBI taxonomy Id: 525318
Other names: L. buchneri ATCC 11577, Lactobacillus buchneri str. ATCC 11577, Lactobacillus buchneri strain ATCC 11577
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