STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvCKetol-acid reductoisomerase; COG: COG0059; Pfam: PF07991,PF01450; InterPro: IPR013023. (348 aa)    
Predicted Functional Partners:
ilvD
Dihydroxy-acid dehydratase; COG: COG0129; Pfam: PF00920; InterPro: IPR000581.
 
 
 0.997
ilvB
Acetolactate synthase, large subunit, biosynthetic type; COG: COG0028; Pfam: PF02776,PF00205,PF02775; InterPro: IPR012846.
 
 
 0.985
leuC
3-isopropylmalate dehydratase, large subunit; COG: COG0065; Pfam: PF00330; InterPro: IPR004430.
 
  
 0.924
leuB
3-isopropylmalate dehydrogenase; COG: COG0473; Pfam: PF00180; InterPro: IPR004429.
 
  
 0.923
alsS
Acetolactate synthase, catabolic; COG: COG0028; Pfam: PF02776,PF00205,PF02775; InterPro: IPR012782.
 
 
 0.917
leuA
2-isopropylmalate synthase; COG: COG0119; Pfam: PF00682; InterPro: IPR013785.
 
  
 0.915
leuD
3-isopropylmalate dehydratase, small subunit; COG: COG0066; Pfam: PF00694; InterPro: IPR004431.
 
  
 0.912
gltA
Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785.
  
  
 0.851
EEI18588.1
Putative pyruvate oxidase; COG: COG0028; Pfam: PF02776,PF00205,PF02775; InterPro: IPR012001.
 
 
 0.848
EEI19084.1
Putative pyruvate oxidase; COG: COG0028; Pfam: PF02776,PF00205,PF02775; InterPro: IPR012001.
 
 
 0.842
Your Current Organism:
Lactobacillus buchneri ATCC 11577
NCBI taxonomy Id: 525318
Other names: L. buchneri ATCC 11577, Lactobacillus buchneri str. ATCC 11577, Lactobacillus buchneri strain ATCC 11577
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.