STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvaDDiphosphomevalonate decarboxylase; COG: COG3407; Pfam: PF00288,PF08544; InterPro: IPR005935. (336 aa)    
Predicted Functional Partners:
mvaK2
Phosphomevalonate kinase; COG: COG1577; Pfam: PF00288,PF08544; InterPro: IPR005917.
 
 0.999
mvk
Mevalonate kinase; COG: COG1577; Pfam: PF00288,PF08544; InterPro: IPR006205.
 
 
 0.997
fni
Isopentenyl-diphosphate delta-isomerase, type 2; COG: COG1304; Pfam: PF01645; InterPro: IPR011179.
 
  
 0.996
mvaA
hydroxymethylglutaryl-CoA reductase, degradative; COG: COG1257; InterPro: IPR004553.
 
 
 0.939
EEI18854.1
hydroxymethylglutaryl-CoA synthase; COG: COG3425; Pfam: PF01154,PF08540; InterPro: IPR011554.
 
 
 0.935
ispA
Polyprenyl synthetase; COG: COG0142; Pfam: PF00348; InterPro: IPR008949.
  
 0.924
uppS
Di-trans,poly-cis-decaprenylcistransferase; COG: COG0020; Pfam: PF01255; InterPro: IPR001441.
   
 0.715
hepT
Polyprenyl synthetase; COG: COG0142; Pfam: PF00348; InterPro: IPR000092.
  
 0.623
lysS
lysine--tRNA ligase; COG: COG1190; Pfam: PF01336,PF00152; InterPro: IPR002313.
 
      0.615
metF
Methylenetetrahydrofolate reductase (NAD(P)H); COG: COG0685; Pfam: PF02219; InterPro: IPR003171.
     
 0.611
Your Current Organism:
Lactobacillus buchneri ATCC 11577
NCBI taxonomy Id: 525318
Other names: L. buchneri ATCC 11577, Lactobacillus buchneri str. ATCC 11577, Lactobacillus buchneri strain ATCC 11577
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