| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEJ72301.1 | EEJ72688.1 | HMPREF0548_0823 | HMPREF0548_0452 | Polyprenyl synthetase; COG: COG0142; Belongs to the FPP/GGPP synthase family. | Polyprenyl synthetase; COG: COG0142; Belongs to the FPP/GGPP synthase family. | 0.945 |
| EEJ72301.1 | fni | HMPREF0548_0823 | HMPREF0548_0049 | Polyprenyl synthetase; COG: COG0142; Belongs to the FPP/GGPP synthase family. | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.951 |
| EEJ72301.1 | mvaA | HMPREF0548_0823 | HMPREF0548_0662 | Polyprenyl synthetase; COG: COG0142; Belongs to the FPP/GGPP synthase family. | hydroxymethylglutaryl-CoA reductase, degradative; COG: COG1257; Belongs to the HMG-CoA reductase family. | 0.513 |
| EEJ72301.1 | mvaD | HMPREF0548_0823 | HMPREF0548_0047 | Polyprenyl synthetase; COG: COG0142; Belongs to the FPP/GGPP synthase family. | Diphosphomevalonate decarboxylase; COG: COG3407. | 0.960 |
| EEJ72688.1 | EEJ72301.1 | HMPREF0548_0452 | HMPREF0548_0823 | Polyprenyl synthetase; COG: COG0142; Belongs to the FPP/GGPP synthase family. | Polyprenyl synthetase; COG: COG0142; Belongs to the FPP/GGPP synthase family. | 0.945 |
| EEJ72688.1 | fni | HMPREF0548_0452 | HMPREF0548_0049 | Polyprenyl synthetase; COG: COG0142; Belongs to the FPP/GGPP synthase family. | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.721 |
| EEJ72688.1 | mvaA | HMPREF0548_0452 | HMPREF0548_0662 | Polyprenyl synthetase; COG: COG0142; Belongs to the FPP/GGPP synthase family. | hydroxymethylglutaryl-CoA reductase, degradative; COG: COG1257; Belongs to the HMG-CoA reductase family. | 0.513 |
| EEJ72688.1 | mvaD | HMPREF0548_0452 | HMPREF0548_0047 | Polyprenyl synthetase; COG: COG0142; Belongs to the FPP/GGPP synthase family. | Diphosphomevalonate decarboxylase; COG: COG3407. | 0.678 |
| EEJ73067.1 | fni | HMPREF0548_0048 | HMPREF0548_0049 | Phosphomevalonate kinase; COG: COG1577. | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.996 |
| EEJ73067.1 | hmcS | HMPREF0548_0048 | HMPREF0548_0663 | Phosphomevalonate kinase; COG: COG1577. | hydroxymethylglutaryl-CoA synthase; COG: COG3425. | 0.917 |
| EEJ73067.1 | mvaA | HMPREF0548_0048 | HMPREF0548_0662 | Phosphomevalonate kinase; COG: COG1577. | hydroxymethylglutaryl-CoA reductase, degradative; COG: COG1257; Belongs to the HMG-CoA reductase family. | 0.909 |
| EEJ73067.1 | mvaD | HMPREF0548_0048 | HMPREF0548_0047 | Phosphomevalonate kinase; COG: COG1577. | Diphosphomevalonate decarboxylase; COG: COG3407. | 0.999 |
| EEJ73067.1 | mvk | HMPREF0548_0048 | HMPREF0548_0046 | Phosphomevalonate kinase; COG: COG1577. | Mevalonate kinase; COG: COG1577. | 0.998 |
| fni | EEJ72301.1 | HMPREF0548_0049 | HMPREF0548_0823 | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Polyprenyl synthetase; COG: COG0142; Belongs to the FPP/GGPP synthase family. | 0.951 |
| fni | EEJ72688.1 | HMPREF0548_0049 | HMPREF0548_0452 | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Polyprenyl synthetase; COG: COG0142; Belongs to the FPP/GGPP synthase family. | 0.721 |
| fni | EEJ73067.1 | HMPREF0548_0049 | HMPREF0548_0048 | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Phosphomevalonate kinase; COG: COG1577. | 0.996 |
| fni | guaA | HMPREF0548_0049 | HMPREF0548_1982 | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.899 |
| fni | hmcS | HMPREF0548_0049 | HMPREF0548_0663 | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | hydroxymethylglutaryl-CoA synthase; COG: COG3425. | 0.873 |
| fni | lctP | HMPREF0548_0049 | HMPREF0548_1571 | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Transporter, lactate permease (LctP) family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. | 0.622 |
| fni | mvaA | HMPREF0548_0049 | HMPREF0548_0662 | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | hydroxymethylglutaryl-CoA reductase, degradative; COG: COG1257; Belongs to the HMG-CoA reductase family. | 0.836 |