| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEJ71447.1 | srtA | HMPREF0548_1677 | HMPREF0548_0109 | LPXTG-motif cell wall anchor domain protein. | Sortase family protein; COG: COG3764. | 0.507 |
| EEJ71475.1 | srtA | HMPREF0548_1674 | HMPREF0548_0109 | Gram-positive signal peptide protein, YSIRK family. | Sortase family protein; COG: COG3764. | 0.507 |
| EEJ71823.1 | srtA | HMPREF0548_1317 | HMPREF0548_0109 | LPXTG-motif cell wall anchor domain protein. | Sortase family protein; COG: COG3764. | 0.498 |
| EEJ72882.1 | srtA | HMPREF0548_0207 | HMPREF0548_0109 | Sugar transport protein; COG: COG4975. | Sortase family protein; COG: COG3764. | 0.489 |
| EEJ72994.1 | lepA | HMPREF0548_0111 | HMPREF0548_0110 | Hypothetical protein. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.481 |
| EEJ72994.1 | srtA | HMPREF0548_0111 | HMPREF0548_0109 | Hypothetical protein. | Sortase family protein; COG: COG3764. | 0.481 |
| apt | lepA | HMPREF0548_0107 | HMPREF0548_0110 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.612 |
| apt | recJ | HMPREF0548_0107 | HMPREF0548_0108 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | single-stranded-DNA-specific exonuclease RecJ; COG: COG0608. | 0.726 |
| apt | srtA | HMPREF0548_0107 | HMPREF0548_0109 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Sortase family protein; COG: COG3764. | 0.528 |
| birA1 | lepA | HMPREF0548_0270 | HMPREF0548_0110 | biotin--[acetyl-CoA-carboxylase] ligase; COG: COG0340. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.691 |
| birA1 | srtA | HMPREF0548_0270 | HMPREF0548_0109 | biotin--[acetyl-CoA-carboxylase] ligase; COG: COG0340. | Sortase family protein; COG: COG3764. | 0.504 |
| lepA | EEJ72994.1 | HMPREF0548_0110 | HMPREF0548_0111 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Hypothetical protein. | 0.481 |
| lepA | apt | HMPREF0548_0110 | HMPREF0548_0107 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.612 |
| lepA | birA1 | HMPREF0548_0110 | HMPREF0548_0270 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | biotin--[acetyl-CoA-carboxylase] ligase; COG: COG0340. | 0.691 |
| lepA | recJ | HMPREF0548_0110 | HMPREF0548_0108 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | single-stranded-DNA-specific exonuclease RecJ; COG: COG0608. | 0.836 |
| lepA | srtA | HMPREF0548_0110 | HMPREF0548_0109 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Sortase family protein; COG: COG3764. | 0.797 |
| lspA | srtA | HMPREF0548_0029 | HMPREF0548_0109 | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Sortase family protein; COG: COG3764. | 0.710 |
| recJ | apt | HMPREF0548_0108 | HMPREF0548_0107 | single-stranded-DNA-specific exonuclease RecJ; COG: COG0608. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.726 |
| recJ | lepA | HMPREF0548_0108 | HMPREF0548_0110 | single-stranded-DNA-specific exonuclease RecJ; COG: COG0608. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.836 |
| recJ | srtA | HMPREF0548_0108 | HMPREF0548_0109 | single-stranded-DNA-specific exonuclease RecJ; COG: COG0608. | Sortase family protein; COG: COG3764. | 0.812 |