| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEJ73046.1 | argF | HMPREF0548_0027 | HMPREF0548_0096 | Putative carbamoyl-phosphate synthase, small subunit; COG: COG0505. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.937 |
| EEJ73046.1 | carB | HMPREF0548_0027 | HMPREF0548_0208 | Putative carbamoyl-phosphate synthase, small subunit; COG: COG0505. | Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | 0.999 |
| EEJ73046.1 | glmS | HMPREF0548_0027 | HMPREF0548_0476 | Putative carbamoyl-phosphate synthase, small subunit; COG: COG0505. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.901 |
| EEJ73046.1 | glnA | HMPREF0548_0027 | HMPREF0548_0318 | Putative carbamoyl-phosphate synthase, small subunit; COG: COG0505. | Glutamine synthetase, type I; COG: COG0174. | 0.915 |
| EEJ73046.1 | pyrB | HMPREF0548_0027 | HMPREF0548_0211 | Putative carbamoyl-phosphate synthase, small subunit; COG: COG0505. | Aspartate carbamoyltransferase; COG: COG0540; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| EEJ73046.1 | pyrC | HMPREF0548_0027 | HMPREF0548_0210 | Putative carbamoyl-phosphate synthase, small subunit; COG: COG0505. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.996 |
| EEJ73046.1 | pyrD | HMPREF0548_0027 | HMPREF0548_0213 | Putative carbamoyl-phosphate synthase, small subunit; COG: COG0505. | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. | 0.791 |
| EEJ73046.1 | pyrE | HMPREF0548_0027 | HMPREF0548_0215 | Putative carbamoyl-phosphate synthase, small subunit; COG: COG0505. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.729 |
| EEJ73046.1 | pyrF | HMPREF0548_0027 | HMPREF0548_0214 | Putative carbamoyl-phosphate synthase, small subunit; COG: COG0505. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.920 |
| argF | EEJ73046.1 | HMPREF0548_0096 | HMPREF0548_0027 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Putative carbamoyl-phosphate synthase, small subunit; COG: COG0505. | 0.937 |
| argF | carA | HMPREF0548_0096 | HMPREF0548_0209 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Belongs to the CarA family. | 0.948 |
| argF | carB | HMPREF0548_0096 | HMPREF0548_0208 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | 0.990 |
| argF | glmS | HMPREF0548_0096 | HMPREF0548_0476 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.519 |
| argF | glnA | HMPREF0548_0096 | HMPREF0548_0318 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Glutamine synthetase, type I; COG: COG0174. | 0.893 |
| argF | pyrB | HMPREF0548_0096 | HMPREF0548_0211 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Aspartate carbamoyltransferase; COG: COG0540; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.956 |
| carA | argF | HMPREF0548_0209 | HMPREF0548_0096 | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Belongs to the CarA family. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.948 |
| carA | carB | HMPREF0548_0209 | HMPREF0548_0208 | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Belongs to the CarA family. | Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | 0.999 |
| carA | glmS | HMPREF0548_0209 | HMPREF0548_0476 | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Belongs to the CarA family. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.901 |
| carA | glnA | HMPREF0548_0209 | HMPREF0548_0318 | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Belongs to the CarA family. | Glutamine synthetase, type I; COG: COG0174. | 0.915 |
| carA | pyrB | HMPREF0548_0209 | HMPREF0548_0211 | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Belongs to the CarA family. | Aspartate carbamoyltransferase; COG: COG0540; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |