| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEJ73045.1 | arcC | HMPREF0548_0026 | HMPREF0548_0095 | Putative carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | Carbamate kinase; COG: COG0549; Belongs to the carbamate kinase family. | 0.893 |
| EEJ73045.1 | argF | HMPREF0548_0026 | HMPREF0548_0096 | Putative carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.948 |
| EEJ73045.1 | carA | HMPREF0548_0026 | HMPREF0548_0209 | Putative carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Belongs to the CarA family. | 0.999 |
| EEJ73045.1 | glmS | HMPREF0548_0026 | HMPREF0548_0476 | Putative carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.918 |
| EEJ73045.1 | glnA | HMPREF0548_0026 | HMPREF0548_0318 | Putative carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | Glutamine synthetase, type I; COG: COG0174. | 0.912 |
| EEJ73045.1 | pyrB | HMPREF0548_0026 | HMPREF0548_0211 | Putative carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | Aspartate carbamoyltransferase; COG: COG0540; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| EEJ73045.1 | pyrC | HMPREF0548_0026 | HMPREF0548_0210 | Putative carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.997 |
| EEJ73045.1 | pyrD | HMPREF0548_0026 | HMPREF0548_0213 | Putative carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. | 0.902 |
| EEJ73045.1 | pyrF | HMPREF0548_0026 | HMPREF0548_0214 | Putative carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.960 |
| arcC | EEJ73045.1 | HMPREF0548_0095 | HMPREF0548_0026 | Carbamate kinase; COG: COG0549; Belongs to the carbamate kinase family. | Putative carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | 0.893 |
| arcC | argF | HMPREF0548_0095 | HMPREF0548_0096 | Carbamate kinase; COG: COG0549; Belongs to the carbamate kinase family. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.999 |
| arcC | carA | HMPREF0548_0095 | HMPREF0548_0209 | Carbamate kinase; COG: COG0549; Belongs to the carbamate kinase family. | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Belongs to the CarA family. | 0.893 |
| arcC | carB | HMPREF0548_0095 | HMPREF0548_0208 | Carbamate kinase; COG: COG0549; Belongs to the carbamate kinase family. | Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | 0.893 |
| arcC | glnA | HMPREF0548_0095 | HMPREF0548_0318 | Carbamate kinase; COG: COG0549; Belongs to the carbamate kinase family. | Glutamine synthetase, type I; COG: COG0174. | 0.947 |
| arcC | pyrB | HMPREF0548_0095 | HMPREF0548_0211 | Carbamate kinase; COG: COG0549; Belongs to the carbamate kinase family. | Aspartate carbamoyltransferase; COG: COG0540; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.952 |
| argF | EEJ73045.1 | HMPREF0548_0096 | HMPREF0548_0026 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Putative carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | 0.948 |
| argF | arcC | HMPREF0548_0096 | HMPREF0548_0095 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Carbamate kinase; COG: COG0549; Belongs to the carbamate kinase family. | 0.999 |
| argF | carA | HMPREF0548_0096 | HMPREF0548_0209 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Belongs to the CarA family. | 0.948 |
| argF | carB | HMPREF0548_0096 | HMPREF0548_0208 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family. | 0.990 |
| argF | glmS | HMPREF0548_0096 | HMPREF0548_0476 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.519 |