| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEJ72755.1 | EEJ72756.1 | HMPREF0548_0355 | HMPREF0548_0356 | Putative primosomal protein DnaI; COG: COG1484. | Replication initiation and membrane attachment protein, DnaB/DnaD family. | 0.931 |
| EEJ72755.1 | EEJ72761.1 | HMPREF0548_0355 | HMPREF0548_0361 | Putative primosomal protein DnaI; COG: COG1484. | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | 0.459 |
| EEJ72755.1 | EEJ72762.1 | HMPREF0548_0355 | HMPREF0548_0362 | Putative primosomal protein DnaI; COG: COG1484. | Transcriptional regulator, MarR family. | 0.459 |
| EEJ72755.1 | EEJ72764.1 | HMPREF0548_0355 | HMPREF0548_0364 | Putative primosomal protein DnaI; COG: COG1484. | Addiction module antitoxin, RelB/DinJ family. | 0.407 |
| EEJ72755.1 | coaE | HMPREF0548_0355 | HMPREF0548_0358 | Putative primosomal protein DnaI; COG: COG1484. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.826 |
| EEJ72755.1 | mutM | HMPREF0548_0355 | HMPREF0548_0359 | Putative primosomal protein DnaI; COG: COG1484. | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.881 |
| EEJ72755.1 | nrdR | HMPREF0548_0355 | HMPREF0548_0357 | Putative primosomal protein DnaI; COG: COG1484. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.811 |
| EEJ72755.1 | polA | HMPREF0548_0355 | HMPREF0548_0360 | Putative primosomal protein DnaI; COG: COG1484. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.902 |
| EEJ72756.1 | EEJ72755.1 | HMPREF0548_0356 | HMPREF0548_0355 | Replication initiation and membrane attachment protein, DnaB/DnaD family. | Putative primosomal protein DnaI; COG: COG1484. | 0.931 |
| EEJ72756.1 | EEJ72761.1 | HMPREF0548_0356 | HMPREF0548_0361 | Replication initiation and membrane attachment protein, DnaB/DnaD family. | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | 0.490 |
| EEJ72756.1 | EEJ72762.1 | HMPREF0548_0356 | HMPREF0548_0362 | Replication initiation and membrane attachment protein, DnaB/DnaD family. | Transcriptional regulator, MarR family. | 0.490 |
| EEJ72756.1 | EEJ72764.1 | HMPREF0548_0356 | HMPREF0548_0364 | Replication initiation and membrane attachment protein, DnaB/DnaD family. | Addiction module antitoxin, RelB/DinJ family. | 0.424 |
| EEJ72756.1 | coaE | HMPREF0548_0356 | HMPREF0548_0358 | Replication initiation and membrane attachment protein, DnaB/DnaD family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.859 |
| EEJ72756.1 | mutM | HMPREF0548_0356 | HMPREF0548_0359 | Replication initiation and membrane attachment protein, DnaB/DnaD family. | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.895 |
| EEJ72756.1 | nrdR | HMPREF0548_0356 | HMPREF0548_0357 | Replication initiation and membrane attachment protein, DnaB/DnaD family. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.929 |
| EEJ72756.1 | polA | HMPREF0548_0356 | HMPREF0548_0360 | Replication initiation and membrane attachment protein, DnaB/DnaD family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.875 |
| EEJ72761.1 | EEJ72755.1 | HMPREF0548_0361 | HMPREF0548_0355 | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | Putative primosomal protein DnaI; COG: COG1484. | 0.459 |
| EEJ72761.1 | EEJ72756.1 | HMPREF0548_0361 | HMPREF0548_0356 | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | Replication initiation and membrane attachment protein, DnaB/DnaD family. | 0.490 |
| EEJ72761.1 | EEJ72762.1 | HMPREF0548_0361 | HMPREF0548_0362 | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | Transcriptional regulator, MarR family. | 0.877 |
| EEJ72761.1 | EEJ72763.1 | HMPREF0548_0361 | HMPREF0548_0363 | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | SPFH/Band 7/PHB domain protein; COG: COG0330. | 0.518 |