node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEJ72761.1 | EEJ72762.1 | HMPREF0548_0361 | HMPREF0548_0362 | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | Transcriptional regulator, MarR family. | 0.877 |
EEJ72761.1 | EEJ72763.1 | HMPREF0548_0361 | HMPREF0548_0363 | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | SPFH/Band 7/PHB domain protein; COG: COG0330. | 0.518 |
EEJ72761.1 | coaE | HMPREF0548_0361 | HMPREF0548_0358 | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.497 |
EEJ72761.1 | mutM | HMPREF0548_0361 | HMPREF0548_0359 | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.498 |
EEJ72761.1 | nrdR | HMPREF0548_0361 | HMPREF0548_0357 | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.490 |
EEJ72762.1 | EEJ72761.1 | HMPREF0548_0362 | HMPREF0548_0361 | Transcriptional regulator, MarR family. | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | 0.877 |
EEJ72762.1 | EEJ72763.1 | HMPREF0548_0362 | HMPREF0548_0363 | Transcriptional regulator, MarR family. | SPFH/Band 7/PHB domain protein; COG: COG0330. | 0.621 |
EEJ72762.1 | bglP2 | HMPREF0548_0362 | HMPREF0548_0754 | Transcriptional regulator, MarR family. | PTS system, beta-glucoside-specific, IIABC component; COG: COG1263. | 0.909 |
EEJ72762.1 | coaE | HMPREF0548_0362 | HMPREF0548_0358 | Transcriptional regulator, MarR family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.618 |
EEJ72762.1 | glvC | HMPREF0548_0362 | HMPREF0548_0643 | Transcriptional regulator, MarR family. | PTS system maltose-specific EIICB component; COG: COG1263. | 0.649 |
EEJ72762.1 | mutM | HMPREF0548_0362 | HMPREF0548_0359 | Transcriptional regulator, MarR family. | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.501 |
EEJ72762.1 | nrdR | HMPREF0548_0362 | HMPREF0548_0357 | Transcriptional regulator, MarR family. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.503 |
EEJ72762.1 | sacP | HMPREF0548_0362 | HMPREF0548_1087 | Transcriptional regulator, MarR family. | Phosphotransferase system, EIIC; COG: COG1263. | 0.649 |
EEJ72762.1 | scrA | HMPREF0548_0362 | HMPREF0548_2152 | Transcriptional regulator, MarR family. | PTS system sucrose-specific IIBC component; COG: COG1263. | 0.909 |
EEJ72762.1 | treB | HMPREF0548_0362 | HMPREF0548_1063 | Transcriptional regulator, MarR family. | Phosphotransferase system, EIIC; COG: COG1263. | 0.909 |
EEJ72763.1 | EEJ72761.1 | HMPREF0548_0363 | HMPREF0548_0361 | SPFH/Band 7/PHB domain protein; COG: COG0330. | Drug resistance MFS transporter, drug:H+ antiporter-2 family; COG: COG0477; Belongs to the major facilitator superfamily. | 0.518 |
EEJ72763.1 | EEJ72762.1 | HMPREF0548_0363 | HMPREF0548_0362 | SPFH/Band 7/PHB domain protein; COG: COG0330. | Transcriptional regulator, MarR family. | 0.621 |
bglP2 | EEJ72762.1 | HMPREF0548_0754 | HMPREF0548_0362 | PTS system, beta-glucoside-specific, IIABC component; COG: COG1263. | Transcriptional regulator, MarR family. | 0.909 |
bglP2 | glvC | HMPREF0548_0754 | HMPREF0548_0643 | PTS system, beta-glucoside-specific, IIABC component; COG: COG1263. | PTS system maltose-specific EIICB component; COG: COG1263. | 0.999 |
bglP2 | sacP | HMPREF0548_0754 | HMPREF0548_1087 | PTS system, beta-glucoside-specific, IIABC component; COG: COG1263. | Phosphotransferase system, EIIC; COG: COG1263. | 0.995 |