node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEJ71989.1 | EEJ72782.1 | HMPREF0548_1231 | HMPREF0548_0382 | SNF2 family N-terminal domain protein; COG: COG0553. | Hypothetical protein. | 0.746 |
EEJ71989.1 | dinB | HMPREF0548_1231 | HMPREF0548_2179 | SNF2 family N-terminal domain protein; COG: COG0553. | ImpB/MucB/SamB family protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.746 |
EEJ71989.1 | dinB2 | HMPREF0548_1231 | HMPREF0548_0383 | SNF2 family N-terminal domain protein; COG: COG0553. | ImpB/MucB/SamB family protein; COG: COG0389. | 0.746 |
EEJ71989.1 | dnaN | HMPREF0548_1231 | HMPREF0548_1360 | SNF2 family N-terminal domain protein; COG: COG0553. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.889 |
EEJ71989.1 | polA | HMPREF0548_1231 | HMPREF0548_0360 | SNF2 family N-terminal domain protein; COG: COG0553. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.998 |
EEJ71989.1 | recA | HMPREF0548_1231 | HMPREF0548_0700 | SNF2 family N-terminal domain protein; COG: COG0553. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.860 |
EEJ72781.1 | EEJ72782.1 | HMPREF0548_0381 | HMPREF0548_0382 | Hypothetical protein. | Hypothetical protein. | 0.960 |
EEJ72781.1 | dinB2 | HMPREF0548_0381 | HMPREF0548_0383 | Hypothetical protein. | ImpB/MucB/SamB family protein; COG: COG0389. | 0.959 |
EEJ72782.1 | EEJ71989.1 | HMPREF0548_0382 | HMPREF0548_1231 | Hypothetical protein. | SNF2 family N-terminal domain protein; COG: COG0553. | 0.746 |
EEJ72782.1 | EEJ72781.1 | HMPREF0548_0382 | HMPREF0548_0381 | Hypothetical protein. | Hypothetical protein. | 0.960 |
EEJ72782.1 | dinB | HMPREF0548_0382 | HMPREF0548_2179 | Hypothetical protein. | ImpB/MucB/SamB family protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.580 |
EEJ72782.1 | dinB2 | HMPREF0548_0382 | HMPREF0548_0383 | Hypothetical protein. | ImpB/MucB/SamB family protein; COG: COG0389. | 0.992 |
EEJ72782.1 | dnaN | HMPREF0548_0382 | HMPREF0548_1360 | Hypothetical protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.871 |
EEJ72782.1 | ftsW | HMPREF0548_0382 | HMPREF0548_0886 | Hypothetical protein. | Cell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772; Belongs to the SEDS family. | 0.752 |
EEJ72782.1 | lexA | HMPREF0548_0382 | HMPREF0548_0143 | Hypothetical protein. | Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.806 |
EEJ72782.1 | polA | HMPREF0548_0382 | HMPREF0548_0360 | Hypothetical protein. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.706 |
EEJ72782.1 | recA | HMPREF0548_0382 | HMPREF0548_0700 | Hypothetical protein. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.842 |
EEJ72782.1 | rodA | HMPREF0548_0382 | HMPREF0548_0187 | Hypothetical protein. | Cell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772; Belongs to the SEDS family. | 0.784 |
dinB | EEJ71989.1 | HMPREF0548_2179 | HMPREF0548_1231 | ImpB/MucB/SamB family protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | SNF2 family N-terminal domain protein; COG: COG0553. | 0.746 |
dinB | EEJ72782.1 | HMPREF0548_2179 | HMPREF0548_0382 | ImpB/MucB/SamB family protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Hypothetical protein. | 0.580 |