| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEJ71154.1 | EEJ72743.1 | HMPREF0548_2097 | HMPREF0548_0343 | RNA methyltransferase, TrmH family, group 3; COG: COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Iojap-like protein. | 0.784 |
| EEJ71154.1 | EEJ72790.1 | HMPREF0548_2097 | HMPREF0548_0390 | RNA methyltransferase, TrmH family, group 3; COG: COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Pseudouridine synthase, RluA family; COG: COG0564. | 0.836 |
| EEJ71154.1 | cgtA | HMPREF0548_2097 | HMPREF0548_0994 | RNA methyltransferase, TrmH family, group 3; COG: COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.657 |
| EEJ71154.1 | rplM | HMPREF0548_2097 | HMPREF0548_2075 | RNA methyltransferase, TrmH family, group 3; COG: COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.837 |
| EEJ71154.1 | rplN | HMPREF0548_2097 | HMPREF0548_2053 | RNA methyltransferase, TrmH family, group 3; COG: COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.772 |
| EEJ71154.1 | rplO | HMPREF0548_2097 | HMPREF0548_2062 | RNA methyltransferase, TrmH family, group 3; COG: COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.781 |
| EEJ71154.1 | rplQ | HMPREF0548_2097 | HMPREF0548_2070 | RNA methyltransferase, TrmH family, group 3; COG: COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosomal protein L17; COG: COG0203. | 0.790 |
| EEJ71154.1 | rplU | HMPREF0548_2097 | HMPREF0548_0814 | RNA methyltransferase, TrmH family, group 3; COG: COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.781 |
| EEJ71154.1 | trmE | HMPREF0548_2097 | HMPREF0548_1365 | RNA methyltransferase, TrmH family, group 3; COG: COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.789 |
| EEJ72743.1 | EEJ71154.1 | HMPREF0548_0343 | HMPREF0548_2097 | Iojap-like protein. | RNA methyltransferase, TrmH family, group 3; COG: COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.784 |
| EEJ72743.1 | EEJ72790.1 | HMPREF0548_0343 | HMPREF0548_0390 | Iojap-like protein. | Pseudouridine synthase, RluA family; COG: COG0564. | 0.795 |
| EEJ72743.1 | EEJ72875.1 | HMPREF0548_0343 | HMPREF0548_0336 | Iojap-like protein. | RNA methyltransferase, TrmH family; COG: COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.790 |
| EEJ72743.1 | cgtA | HMPREF0548_0343 | HMPREF0548_0994 | Iojap-like protein. | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.874 |
| EEJ72743.1 | rplM | HMPREF0548_0343 | HMPREF0548_2075 | Iojap-like protein. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
| EEJ72743.1 | rplN | HMPREF0548_0343 | HMPREF0548_2053 | Iojap-like protein. | Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.999 |
| EEJ72743.1 | rplO | HMPREF0548_0343 | HMPREF0548_2062 | Iojap-like protein. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.999 |
| EEJ72743.1 | rplQ | HMPREF0548_0343 | HMPREF0548_2070 | Iojap-like protein. | Ribosomal protein L17; COG: COG0203. | 0.999 |
| EEJ72743.1 | rplU | HMPREF0548_0343 | HMPREF0548_0814 | Iojap-like protein. | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.999 |
| EEJ72743.1 | trmE | HMPREF0548_0343 | HMPREF0548_1365 | Iojap-like protein. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.805 |
| EEJ72790.1 | EEJ71154.1 | HMPREF0548_0390 | HMPREF0548_2097 | Pseudouridine synthase, RluA family; COG: COG0564. | RNA methyltransferase, TrmH family, group 3; COG: COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.836 |