| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEJ71328.1 | EEJ72663.1 | HMPREF0548_1787 | HMPREF0548_0487 | Transcriptional regulator, Sir2 family; COG: COG0846. | Isochorismatase family protein; COG: COG1335. | 0.578 |
| EEJ71328.1 | EEJ72720.1 | HMPREF0548_1787 | HMPREF0548_0416 | Transcriptional regulator, Sir2 family; COG: COG0846. | Isochorismatase family protein; COG: COG1335. | 0.540 |
| EEJ71328.1 | mtnN | HMPREF0548_1787 | HMPREF0548_0871 | Transcriptional regulator, Sir2 family; COG: COG0846. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.424 |
| EEJ71328.1 | pncB | HMPREF0548_1787 | HMPREF0548_0415 | Transcriptional regulator, Sir2 family; COG: COG0846. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.460 |
| EEJ71328.1 | pncB-2 | HMPREF0548_1787 | HMPREF0548_0554 | Transcriptional regulator, Sir2 family; COG: COG0846. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.460 |
| EEJ72663.1 | EEJ71328.1 | HMPREF0548_0487 | HMPREF0548_1787 | Isochorismatase family protein; COG: COG1335. | Transcriptional regulator, Sir2 family; COG: COG0846. | 0.578 |
| EEJ72663.1 | EEJ72720.1 | HMPREF0548_0487 | HMPREF0548_0416 | Isochorismatase family protein; COG: COG1335. | Isochorismatase family protein; COG: COG1335. | 0.674 |
| EEJ72663.1 | accB | HMPREF0548_0487 | HMPREF0548_0276 | Isochorismatase family protein; COG: COG1335. | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.535 |
| EEJ72663.1 | accC | HMPREF0548_0487 | HMPREF0548_0274 | Isochorismatase family protein; COG: COG1335. | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.496 |
| EEJ72663.1 | birA1 | HMPREF0548_0487 | HMPREF0548_0270 | Isochorismatase family protein; COG: COG1335. | biotin--[acetyl-CoA-carboxylase] ligase; COG: COG0340. | 0.557 |
| EEJ72663.1 | gatA | HMPREF0548_0487 | HMPREF0548_0567 | Isochorismatase family protein; COG: COG1335. | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | 0.555 |
| EEJ72663.1 | mtnN | HMPREF0548_0487 | HMPREF0548_0871 | Isochorismatase family protein; COG: COG1335. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.536 |
| EEJ72663.1 | pncB | HMPREF0548_0487 | HMPREF0548_0415 | Isochorismatase family protein; COG: COG1335. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.530 |
| EEJ72663.1 | pncB-2 | HMPREF0548_0487 | HMPREF0548_0554 | Isochorismatase family protein; COG: COG1335. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.530 |
| EEJ72718.1 | EEJ72720.1 | HMPREF0548_0414 | HMPREF0548_0416 | Hydrolase, NUDIX family; COG: COG1051. | Isochorismatase family protein; COG: COG1335. | 0.602 |
| EEJ72718.1 | birA1 | HMPREF0548_0414 | HMPREF0548_0270 | Hydrolase, NUDIX family; COG: COG1051. | biotin--[acetyl-CoA-carboxylase] ligase; COG: COG0340. | 0.446 |
| EEJ72718.1 | pncB | HMPREF0548_0414 | HMPREF0548_0415 | Hydrolase, NUDIX family; COG: COG1051. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.723 |
| EEJ72718.1 | pncB-2 | HMPREF0548_0414 | HMPREF0548_0554 | Hydrolase, NUDIX family; COG: COG1051. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.463 |
| EEJ72720.1 | EEJ71328.1 | HMPREF0548_0416 | HMPREF0548_1787 | Isochorismatase family protein; COG: COG1335. | Transcriptional regulator, Sir2 family; COG: COG0846. | 0.540 |
| EEJ72720.1 | EEJ72663.1 | HMPREF0548_0416 | HMPREF0548_0487 | Isochorismatase family protein; COG: COG1335. | Isochorismatase family protein; COG: COG1335. | 0.674 |