| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEJ71439.1 | gutR | HMPREF0548_1700 | HMPREF0548_0619 | Acetyltransferase, GNAT family. | Transcriptional regulator, DeoR family; COG: COG1349. | 0.403 |
| EEJ71558.1 | gutR | HMPREF0548_1578 | HMPREF0548_0619 | Acetyltransferase, GNAT family; COG: COG1670. | Transcriptional regulator, DeoR family; COG: COG1349. | 0.403 |
| deoC | gap | HMPREF0548_2137 | HMPREF0548_0731 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.948 |
| deoC | gutR | HMPREF0548_2137 | HMPREF0548_0619 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Transcriptional regulator, DeoR family; COG: COG1349. | 0.436 |
| deoC | rbsK | HMPREF0548_2137 | HMPREF0548_0613 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.994 |
| fruA | gap | HMPREF0548_1565 | HMPREF0548_0731 | Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COG: COG1299. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.524 |
| fruA | gutR | HMPREF0548_1565 | HMPREF0548_0619 | Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COG: COG1299. | Transcriptional regulator, DeoR family; COG: COG1349. | 0.791 |
| fruA | pfkB | HMPREF0548_1565 | HMPREF0548_1564 | Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COG: COG1299. | 1-phosphofructokinase; COG: COG1105; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.999 |
| fruA | rbsK | HMPREF0548_1565 | HMPREF0548_0613 | Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COG: COG1299. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.982 |
| gap | deoC | HMPREF0548_0731 | HMPREF0548_2137 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.948 |
| gap | fruA | HMPREF0548_0731 | HMPREF0548_1565 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COG: COG1299. | 0.524 |
| gap | gutR | HMPREF0548_0731 | HMPREF0548_0619 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Transcriptional regulator, DeoR family; COG: COG1349. | 0.415 |
| gap | rbsK | HMPREF0548_0731 | HMPREF0548_0613 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.726 |
| gap | rpiA | HMPREF0548_0731 | HMPREF0548_0614 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.680 |
| gutR | EEJ71439.1 | HMPREF0548_0619 | HMPREF0548_1700 | Transcriptional regulator, DeoR family; COG: COG1349. | Acetyltransferase, GNAT family. | 0.403 |
| gutR | EEJ71558.1 | HMPREF0548_0619 | HMPREF0548_1578 | Transcriptional regulator, DeoR family; COG: COG1349. | Acetyltransferase, GNAT family; COG: COG1670. | 0.403 |
| gutR | deoC | HMPREF0548_0619 | HMPREF0548_2137 | Transcriptional regulator, DeoR family; COG: COG1349. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.436 |
| gutR | fruA | HMPREF0548_0619 | HMPREF0548_1565 | Transcriptional regulator, DeoR family; COG: COG1349. | Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COG: COG1299. | 0.791 |
| gutR | gap | HMPREF0548_0619 | HMPREF0548_0731 | Transcriptional regulator, DeoR family; COG: COG1349. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.415 |
| gutR | pfkB | HMPREF0548_0619 | HMPREF0548_1564 | Transcriptional regulator, DeoR family; COG: COG1349. | 1-phosphofructokinase; COG: COG1105; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.825 |