| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEJ72870.1 | eno | HMPREF0548_0331 | HMPREF0548_0939 | Lactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Belongs to the LDH/MDH superfamily. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.492 |
| EEJ72870.1 | fba | HMPREF0548_0331 | HMPREF0548_0406 | Lactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Belongs to the LDH/MDH superfamily. | Putative fructose-1,6-bisphosphate aldolase, class II; COG: COG0191. | 0.948 |
| EEJ72870.1 | gap | HMPREF0548_0331 | HMPREF0548_0731 | Lactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Belongs to the LDH/MDH superfamily. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.759 |
| EEJ72870.1 | gpmA1 | HMPREF0548_0331 | HMPREF0548_1716 | Lactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Belongs to the LDH/MDH superfamily. | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.664 |
| EEJ72870.1 | pgi | HMPREF0548_0331 | HMPREF0548_0794 | Lactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Belongs to the LDH/MDH superfamily. | Glucose-6-phosphate isomerase; COG: COG0166; Belongs to the GPI family. | 0.954 |
| EEJ72870.1 | ppsA | HMPREF0548_0331 | HMPREF0548_0105 | Lactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Belongs to the LDH/MDH superfamily. | Pyruvate, water dikinase; COG: COG0574. | 0.943 |
| EEJ72870.1 | pyk | HMPREF0548_0331 | HMPREF0548_1004 | Lactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Belongs to the LDH/MDH superfamily. | Pyruvate kinase; COG: COG0469; Belongs to the pyruvate kinase family. | 0.990 |
| EEJ72870.1 | tal1 | HMPREF0548_0331 | HMPREF0548_0627 | Lactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Belongs to the LDH/MDH superfamily. | Fructose-6-phosphate aldolase; COG: COG0176. | 0.945 |
| EEJ72870.1 | xfp | HMPREF0548_0331 | HMPREF0548_0640 | Lactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Belongs to the LDH/MDH superfamily. | D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; COG: COG3957. | 0.942 |
| eno | EEJ72870.1 | HMPREF0548_0939 | HMPREF0548_0331 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Lactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Belongs to the LDH/MDH superfamily. | 0.492 |
| eno | fba | HMPREF0548_0939 | HMPREF0548_0406 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Putative fructose-1,6-bisphosphate aldolase, class II; COG: COG0191. | 0.990 |
| eno | gap | HMPREF0548_0939 | HMPREF0548_0731 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.995 |
| eno | gpmA1 | HMPREF0548_0939 | HMPREF0548_1716 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.992 |
| eno | pgi | HMPREF0548_0939 | HMPREF0548_0794 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glucose-6-phosphate isomerase; COG: COG0166; Belongs to the GPI family. | 0.994 |
| eno | ppsA | HMPREF0548_0939 | HMPREF0548_0105 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Pyruvate, water dikinase; COG: COG0574. | 0.959 |
| eno | pyk | HMPREF0548_0939 | HMPREF0548_1004 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Pyruvate kinase; COG: COG0469; Belongs to the pyruvate kinase family. | 0.999 |
| eno | tal1 | HMPREF0548_0939 | HMPREF0548_0627 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Fructose-6-phosphate aldolase; COG: COG0176. | 0.967 |
| eno | tpiA | HMPREF0548_0939 | HMPREF0548_0733 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.992 |
| eno | xfp | HMPREF0548_0939 | HMPREF0548_0640 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; COG: COG3957. | 0.947 |
| fba | EEJ72870.1 | HMPREF0548_0406 | HMPREF0548_0331 | Putative fructose-1,6-bisphosphate aldolase, class II; COG: COG0191. | Lactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Belongs to the LDH/MDH superfamily. | 0.948 |