| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEJ72500.1 | hmcS | HMPREF0548_0624 | HMPREF0548_0663 | Formate C-acetyltransferase; COG: COG1882. | hydroxymethylglutaryl-CoA synthase; COG: COG3425. | 0.892 |
| EEJ72500.1 | thil | HMPREF0548_0624 | HMPREF0548_0661 | Formate C-acetyltransferase; COG: COG1882. | acetyl-CoA C-acetyltransferase; COG: COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | 0.905 |
| EEJ73067.1 | fni | HMPREF0548_0048 | HMPREF0548_0049 | Phosphomevalonate kinase; COG: COG1577. | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.996 |
| EEJ73067.1 | hmcS | HMPREF0548_0048 | HMPREF0548_0663 | Phosphomevalonate kinase; COG: COG1577. | hydroxymethylglutaryl-CoA synthase; COG: COG3425. | 0.917 |
| EEJ73067.1 | mvaA | HMPREF0548_0048 | HMPREF0548_0662 | Phosphomevalonate kinase; COG: COG1577. | hydroxymethylglutaryl-CoA reductase, degradative; COG: COG1257; Belongs to the HMG-CoA reductase family. | 0.909 |
| EEJ73067.1 | mvaD | HMPREF0548_0048 | HMPREF0548_0047 | Phosphomevalonate kinase; COG: COG1577. | Diphosphomevalonate decarboxylase; COG: COG3407. | 0.999 |
| EEJ73067.1 | mvk | HMPREF0548_0048 | HMPREF0548_0046 | Phosphomevalonate kinase; COG: COG1577. | Mevalonate kinase; COG: COG1577. | 0.998 |
| EEJ73067.1 | thil | HMPREF0548_0048 | HMPREF0548_0661 | Phosphomevalonate kinase; COG: COG1577. | acetyl-CoA C-acetyltransferase; COG: COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | 0.582 |
| acpP | acpP-2 | HMPREF0548_0844 | HMPREF0548_0280 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.937 |
| acpP | hmcS | HMPREF0548_0844 | HMPREF0548_0663 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | hydroxymethylglutaryl-CoA synthase; COG: COG3425. | 0.866 |
| acpP | thil | HMPREF0548_0844 | HMPREF0548_0661 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | acetyl-CoA C-acetyltransferase; COG: COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | 0.484 |
| acpP-2 | acpP | HMPREF0548_0280 | HMPREF0548_0844 | Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.937 |
| acpP-2 | hmcS | HMPREF0548_0280 | HMPREF0548_0663 | Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | hydroxymethylglutaryl-CoA synthase; COG: COG3425. | 0.866 |
| acpP-2 | thil | HMPREF0548_0280 | HMPREF0548_0661 | Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | acetyl-CoA C-acetyltransferase; COG: COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | 0.484 |
| fni | EEJ73067.1 | HMPREF0548_0049 | HMPREF0548_0048 | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Phosphomevalonate kinase; COG: COG1577. | 0.996 |
| fni | hmcS | HMPREF0548_0049 | HMPREF0548_0663 | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | hydroxymethylglutaryl-CoA synthase; COG: COG3425. | 0.873 |
| fni | mvaA | HMPREF0548_0049 | HMPREF0548_0662 | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | hydroxymethylglutaryl-CoA reductase, degradative; COG: COG1257; Belongs to the HMG-CoA reductase family. | 0.836 |
| fni | mvaD | HMPREF0548_0049 | HMPREF0548_0047 | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Diphosphomevalonate decarboxylase; COG: COG3407. | 0.996 |
| fni | mvk | HMPREF0548_0049 | HMPREF0548_0046 | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Mevalonate kinase; COG: COG1577. | 0.965 |
| hmcS | EEJ72500.1 | HMPREF0548_0663 | HMPREF0548_0624 | hydroxymethylglutaryl-CoA synthase; COG: COG3425. | Formate C-acetyltransferase; COG: COG1882. | 0.892 |