node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEJ72473.1 | gpsA | HMPREF0548_0709 | HMPREF0548_0712 | Hypothetical protein. | Putative glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.624 |
EEJ72473.1 | hprK | HMPREF0548_0709 | HMPREF0548_0710 | Hypothetical protein. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | 0.732 |
EEJ72473.1 | lgt | HMPREF0548_0709 | HMPREF0548_0711 | Hypothetical protein. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.729 |
EEJ72473.1 | prfB | HMPREF0548_0709 | HMPREF0548_0708 | Hypothetical protein. | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.768 |
EEJ72473.1 | secA | HMPREF0548_0709 | HMPREF0548_0707 | Hypothetical protein. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.456 |
EEJ72877.1 | lgt | HMPREF0548_0338 | HMPREF0548_0711 | Membrane protein insertase, YidC/Oxa1 family; COG: COG0706. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.625 |
EEJ72877.1 | prfB | HMPREF0548_0338 | HMPREF0548_0708 | Membrane protein insertase, YidC/Oxa1 family; COG: COG0706. | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.805 |
EEJ72877.1 | secA | HMPREF0548_0338 | HMPREF0548_0707 | Membrane protein insertase, YidC/Oxa1 family; COG: COG0706. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.972 |
EEJ72877.1 | yidC | HMPREF0548_0338 | HMPREF0548_1364 | Membrane protein insertase, YidC/Oxa1 family; COG: COG0706. | Membrane protein insertase, YidC/Oxa1 family; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. | 0.953 |
alr | lgt | HMPREF0548_2018 | HMPREF0548_0711 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.642 |
gpsA | EEJ72473.1 | HMPREF0548_0712 | HMPREF0548_0709 | Putative glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Hypothetical protein. | 0.624 |
gpsA | hprK | HMPREF0548_0712 | HMPREF0548_0710 | Putative glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | 0.781 |
gpsA | lgt | HMPREF0548_0712 | HMPREF0548_0711 | Putative glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.916 |
gpsA | prfB | HMPREF0548_0712 | HMPREF0548_0708 | Putative glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.719 |
gpsA | secA | HMPREF0548_0712 | HMPREF0548_0707 | Putative glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.451 |
hprK | EEJ72473.1 | HMPREF0548_0710 | HMPREF0548_0709 | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | Hypothetical protein. | 0.732 |
hprK | gpsA | HMPREF0548_0710 | HMPREF0548_0712 | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | Putative glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.781 |
hprK | lgt | HMPREF0548_0710 | HMPREF0548_0711 | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.934 |
hprK | prfB | HMPREF0548_0710 | HMPREF0548_0708 | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.832 |
hprK | secA | HMPREF0548_0710 | HMPREF0548_0707 | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.498 |