| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| adh2 | birA1 | HMPREF0548_0475 | HMPREF0548_0270 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | biotin--[acetyl-CoA-carboxylase] ligase; COG: COG0340. | 0.428 |
| adh2 | glxK | HMPREF0548_0475 | HMPREF0548_0752 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Glycerate kinase; COG: COG1929; Belongs to the glycerate kinase type-1 family. | 0.496 |
| adh2 | gpmA1 | HMPREF0548_0475 | HMPREF0548_1716 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.616 |
| adh2 | gpmA2 | HMPREF0548_0475 | HMPREF0548_2085 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.616 |
| adh2 | gyaR | HMPREF0548_0475 | HMPREF0548_0990 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Glyoxylate reductase; COG: COG0111; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.944 |
| adh2 | ldhA | HMPREF0548_0475 | HMPREF0548_1298 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | D-lactate dehydrogenase; COG: COG1052; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.944 |
| adh2 | tadA | HMPREF0548_0475 | HMPREF0548_2120 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.669 |
| birA1 | adh2 | HMPREF0548_0270 | HMPREF0548_0475 | biotin--[acetyl-CoA-carboxylase] ligase; COG: COG0340. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.428 |
| birA1 | glxK | HMPREF0548_0270 | HMPREF0548_0752 | biotin--[acetyl-CoA-carboxylase] ligase; COG: COG0340. | Glycerate kinase; COG: COG1929; Belongs to the glycerate kinase type-1 family. | 0.505 |
| birA1 | tadA | HMPREF0548_0270 | HMPREF0548_2120 | biotin--[acetyl-CoA-carboxylase] ligase; COG: COG0340. | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.947 |
| glxK | adh2 | HMPREF0548_0752 | HMPREF0548_0475 | Glycerate kinase; COG: COG1929; Belongs to the glycerate kinase type-1 family. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.496 |
| glxK | birA1 | HMPREF0548_0752 | HMPREF0548_0270 | Glycerate kinase; COG: COG1929; Belongs to the glycerate kinase type-1 family. | biotin--[acetyl-CoA-carboxylase] ligase; COG: COG0340. | 0.505 |
| glxK | gpmA1 | HMPREF0548_0752 | HMPREF0548_1716 | Glycerate kinase; COG: COG1929; Belongs to the glycerate kinase type-1 family. | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.937 |
| glxK | gpmA2 | HMPREF0548_0752 | HMPREF0548_2085 | Glycerate kinase; COG: COG1929; Belongs to the glycerate kinase type-1 family. | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.937 |
| glxK | gyaR | HMPREF0548_0752 | HMPREF0548_0990 | Glycerate kinase; COG: COG1929; Belongs to the glycerate kinase type-1 family. | Glyoxylate reductase; COG: COG0111; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.945 |
| glxK | ldhA | HMPREF0548_0752 | HMPREF0548_1298 | Glycerate kinase; COG: COG1929; Belongs to the glycerate kinase type-1 family. | D-lactate dehydrogenase; COG: COG1052; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.536 |
| glxK | licT | HMPREF0548_0752 | HMPREF0548_0753 | Glycerate kinase; COG: COG1929; Belongs to the glycerate kinase type-1 family. | PRD domain protein; COG: COG3711. | 0.493 |
| glxK | murD | HMPREF0548_0752 | HMPREF0548_0858 | Glycerate kinase; COG: COG1929; Belongs to the glycerate kinase type-1 family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.682 |
| glxK | pyrC | HMPREF0548_0752 | HMPREF0548_0210 | Glycerate kinase; COG: COG1929; Belongs to the glycerate kinase type-1 family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.672 |
| glxK | tadA | HMPREF0548_0752 | HMPREF0548_2120 | Glycerate kinase; COG: COG1929; Belongs to the glycerate kinase type-1 family. | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.905 |