STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvEBranched-chain-amino-acid transaminase; COG: COG0115. (341 aa)    
Predicted Functional Partners:
EEJ73104.1
Homoserine dehydrogenase; COG: COG0460.
  
 
 0.965
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.956
EEJ72870.1
Lactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Belongs to the LDH/MDH superfamily.
  
 
 0.944
ldh2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 
 0.906
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 
 0.906
spxB
Pyruvate oxidase; COG: COG0028; Belongs to the TPP enzyme family.
 
 
 0.765
oxc
oxalyl-CoA decarboxylase; COG: COG0028; Belongs to the TPP enzyme family.
  
 
 0.732
dltA
D-alanine--poly(phosphoribitol) ligase, subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]
  
 0.714
ddl
D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
  
 
 0.705
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
 0.705
Your Current Organism:
Lactobacillus ultunensis
NCBI taxonomy Id: 525365
Other names: L. ultunensis DSM 16047, Lactobacillus ultunensis DSM 16047, Lactobacillus ultunensis str. DSM 16047, Lactobacillus ultunensis strain DSM 16047
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