node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEJ72161.1 | dapA | HMPREF0548_0984 | HMPREF0548_0909 | Aminotransferase, class I/II; COG: COG0436. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.651 |
EEJ72161.1 | dapB | HMPREF0548_0984 | HMPREF0548_0910 | Aminotransferase, class I/II; COG: COG0436. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.520 |
EEJ72161.1 | dapD | HMPREF0548_0984 | HMPREF0548_0907 | Aminotransferase, class I/II; COG: COG0436. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.877 |
EEJ72161.1 | dapF | HMPREF0548_0984 | HMPREF0548_0904 | Aminotransferase, class I/II; COG: COG0436. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.670 |
EEJ72161.1 | hipO | HMPREF0548_0984 | HMPREF0548_0908 | Aminotransferase, class I/II; COG: COG0436. | Amidohydrolase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. | 0.864 |
EEJ72161.1 | lysA | HMPREF0548_0984 | HMPREF0548_0906 | Aminotransferase, class I/II; COG: COG0436. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.609 |
EEJ72226.1 | asd | HMPREF0548_0913 | HMPREF0548_0912 | Beta-lactamase; COG: COG1680. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.535 |
EEJ72226.1 | aspC | HMPREF0548_0913 | HMPREF0548_0911 | Beta-lactamase; COG: COG1680. | Aminotransferase, class I/II; COG: COG0436. | 0.538 |
EEJ72226.1 | dapA | HMPREF0548_0913 | HMPREF0548_0909 | Beta-lactamase; COG: COG1680. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.522 |
EEJ72226.1 | dapB | HMPREF0548_0913 | HMPREF0548_0910 | Beta-lactamase; COG: COG1680. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.519 |
EEJ72226.1 | dapD | HMPREF0548_0913 | HMPREF0548_0907 | Beta-lactamase; COG: COG1680. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.518 |
EEJ72226.1 | hipO | HMPREF0548_0913 | HMPREF0548_0908 | Beta-lactamase; COG: COG1680. | Amidohydrolase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. | 0.519 |
EEJ72226.1 | lysA | HMPREF0548_0913 | HMPREF0548_0906 | Beta-lactamase; COG: COG1680. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.508 |
asd | EEJ72226.1 | HMPREF0548_0912 | HMPREF0548_0913 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Beta-lactamase; COG: COG1680. | 0.535 |
asd | aspC | HMPREF0548_0912 | HMPREF0548_0911 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aminotransferase, class I/II; COG: COG0436. | 0.851 |
asd | dapA | HMPREF0548_0912 | HMPREF0548_0909 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.997 |
asd | dapB | HMPREF0548_0912 | HMPREF0548_0910 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.955 |
asd | dapD | HMPREF0548_0912 | HMPREF0548_0907 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.964 |
asd | dapF | HMPREF0548_0912 | HMPREF0548_0904 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.781 |
asd | hipO | HMPREF0548_0912 | HMPREF0548_0908 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Amidohydrolase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. | 0.856 |