| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEJ72045.1 | EEJ72046.1 | HMPREF0548_1095 | HMPREF0548_1096 | Type I restriction modification DNA specificity domain protein. | Site-specific recombinase, phage integrase family; COG: COG0582; Belongs to the 'phage' integrase family. | 0.720 |
| EEJ72045.1 | EEJ72047.1 | HMPREF0548_1095 | HMPREF0548_1097 | Type I restriction modification DNA specificity domain protein. | Hypothetical protein. | 0.782 |
| EEJ72045.1 | hsdM | HMPREF0548_1095 | HMPREF0548_1094 | Type I restriction modification DNA specificity domain protein. | Type I restriction-modification system, M subunit; COG: COG0286. | 0.950 |
| EEJ72045.1 | hsdR | HMPREF0548_1095 | HMPREF0548_1098 | Type I restriction modification DNA specificity domain protein. | Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification. | 0.796 |
| EEJ72046.1 | EEJ72045.1 | HMPREF0548_1096 | HMPREF0548_1095 | Site-specific recombinase, phage integrase family; COG: COG0582; Belongs to the 'phage' integrase family. | Type I restriction modification DNA specificity domain protein. | 0.720 |
| EEJ72046.1 | EEJ72047.1 | HMPREF0548_1096 | HMPREF0548_1097 | Site-specific recombinase, phage integrase family; COG: COG0582; Belongs to the 'phage' integrase family. | Hypothetical protein. | 0.875 |
| EEJ72046.1 | EEJ72469.1 | HMPREF0548_1096 | HMPREF0548_0705 | Site-specific recombinase, phage integrase family; COG: COG0582; Belongs to the 'phage' integrase family. | comF family protein; COG: COG1040. | 0.499 |
| EEJ72046.1 | hsdM | HMPREF0548_1096 | HMPREF0548_1094 | Site-specific recombinase, phage integrase family; COG: COG0582; Belongs to the 'phage' integrase family. | Type I restriction-modification system, M subunit; COG: COG0286. | 0.684 |
| EEJ72046.1 | hsdR | HMPREF0548_1096 | HMPREF0548_1098 | Site-specific recombinase, phage integrase family; COG: COG0582; Belongs to the 'phage' integrase family. | Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification. | 0.847 |
| EEJ72046.1 | polA | HMPREF0548_1096 | HMPREF0548_0360 | Site-specific recombinase, phage integrase family; COG: COG0582; Belongs to the 'phage' integrase family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.403 |
| EEJ72046.1 | pta | HMPREF0548_1096 | HMPREF0548_0737 | Site-specific recombinase, phage integrase family; COG: COG0582; Belongs to the 'phage' integrase family. | Phosphate acetyltransferase; COG: COG0280. | 0.408 |
| EEJ72046.1 | topA | HMPREF0548_1096 | HMPREF0548_1028 | Site-specific recombinase, phage integrase family; COG: COG0582; Belongs to the 'phage' integrase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.453 |
| EEJ72047.1 | EEJ72045.1 | HMPREF0548_1097 | HMPREF0548_1095 | Hypothetical protein. | Type I restriction modification DNA specificity domain protein. | 0.782 |
| EEJ72047.1 | EEJ72046.1 | HMPREF0548_1097 | HMPREF0548_1096 | Hypothetical protein. | Site-specific recombinase, phage integrase family; COG: COG0582; Belongs to the 'phage' integrase family. | 0.875 |
| EEJ72047.1 | hsdM | HMPREF0548_1097 | HMPREF0548_1094 | Hypothetical protein. | Type I restriction-modification system, M subunit; COG: COG0286. | 0.981 |
| EEJ72047.1 | hsdR | HMPREF0548_1097 | HMPREF0548_1098 | Hypothetical protein. | Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification. | 0.988 |
| EEJ72047.1 | polA | HMPREF0548_1097 | HMPREF0548_0360 | Hypothetical protein. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.738 |
| EEJ72047.1 | topA | HMPREF0548_1097 | HMPREF0548_1028 | Hypothetical protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.518 |
| EEJ72469.1 | EEJ72046.1 | HMPREF0548_0705 | HMPREF0548_1096 | comF family protein; COG: COG1040. | Site-specific recombinase, phage integrase family; COG: COG0582; Belongs to the 'phage' integrase family. | 0.499 |
| hsdM | EEJ72045.1 | HMPREF0548_1094 | HMPREF0548_1095 | Type I restriction-modification system, M subunit; COG: COG0286. | Type I restriction modification DNA specificity domain protein. | 0.950 |