| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEJ71194.1 | EEJ71700.1 | HMPREF0548_1926 | HMPREF0548_1421 | Beta-lactamase; COG: COG1680. | MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane. | 0.883 |
| EEJ71194.1 | EEJ71702.1 | HMPREF0548_1926 | HMPREF0548_1423 | Beta-lactamase; COG: COG1680. | DltD C-terminal domain protein; COG: COG3966. | 0.914 |
| EEJ71194.1 | dltA | HMPREF0548_1926 | HMPREF0548_1420 | Beta-lactamase; COG: COG1680. | D-alanine--poly(phosphoribitol) ligase, subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] | 0.859 |
| EEJ71194.1 | dltC | HMPREF0548_1926 | HMPREF0548_1422 | Beta-lactamase; COG: COG1680. | D-alanine--poly(phosphoribitol) ligase, subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.712 |
| EEJ71251.1 | EEJ71700.1 | HMPREF0548_1883 | HMPREF0548_1421 | Arylsulfatase; COG: COG1368. | MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane. | 0.692 |
| EEJ71251.1 | EEJ71702.1 | HMPREF0548_1883 | HMPREF0548_1423 | Arylsulfatase; COG: COG1368. | DltD C-terminal domain protein; COG: COG3966. | 0.419 |
| EEJ71700.1 | EEJ71194.1 | HMPREF0548_1421 | HMPREF0548_1926 | MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane. | Beta-lactamase; COG: COG1680. | 0.883 |
| EEJ71700.1 | EEJ71251.1 | HMPREF0548_1421 | HMPREF0548_1883 | MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane. | Arylsulfatase; COG: COG1368. | 0.692 |
| EEJ71700.1 | EEJ71702.1 | HMPREF0548_1421 | HMPREF0548_1423 | MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane. | DltD C-terminal domain protein; COG: COG3966. | 0.999 |
| EEJ71700.1 | EEJ71703.1 | HMPREF0548_1421 | HMPREF0548_1424 | MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane. | Beta-lactamase. | 0.936 |
| EEJ71700.1 | EEJ71722.1 | HMPREF0548_1421 | HMPREF0548_1443 | MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane. | Hypothetical protein. | 0.663 |
| EEJ71700.1 | acpP | HMPREF0548_1421 | HMPREF0548_0844 | MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.920 |
| EEJ71700.1 | acpP-2 | HMPREF0548_1421 | HMPREF0548_0280 | MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane. | Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.920 |
| EEJ71700.1 | dltA | HMPREF0548_1421 | HMPREF0548_1420 | MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane. | D-alanine--poly(phosphoribitol) ligase, subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] | 0.999 |
| EEJ71700.1 | dltC | HMPREF0548_1421 | HMPREF0548_1422 | MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane. | D-alanine--poly(phosphoribitol) ligase, subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.997 |
| EEJ71700.1 | pbpX | HMPREF0548_1421 | HMPREF0548_1293 | MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane. | Beta-lactamase. | 0.635 |
| EEJ71702.1 | EEJ71194.1 | HMPREF0548_1423 | HMPREF0548_1926 | DltD C-terminal domain protein; COG: COG3966. | Beta-lactamase; COG: COG1680. | 0.914 |
| EEJ71702.1 | EEJ71251.1 | HMPREF0548_1423 | HMPREF0548_1883 | DltD C-terminal domain protein; COG: COG3966. | Arylsulfatase; COG: COG1368. | 0.419 |
| EEJ71702.1 | EEJ71700.1 | HMPREF0548_1423 | HMPREF0548_1421 | DltD C-terminal domain protein; COG: COG3966. | MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane. | 0.999 |
| EEJ71702.1 | EEJ71703.1 | HMPREF0548_1423 | HMPREF0548_1424 | DltD C-terminal domain protein; COG: COG3966. | Beta-lactamase. | 0.991 |