STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEJ71504.1BRCA1 C-terminal domain protein. (183 aa)    
Predicted Functional Partners:
EEJ71503.1
Hypothetical protein.
      0.917
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
 
 
 0.863
leuS
leucine--tRNA ligase; COG: COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.777
EEJ71502.1
Hypothetical protein.
       0.773
pcrA
ATP-dependent DNA helicase PcrA; COG: COG0210.
  
  
 0.682
EEJ71505.1
Hypothetical protein.
       0.665
EEJ72576.1
CamS sex pheromone family protein; COG: COG4851.
  
  
 0.627
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.626
recJ
single-stranded-DNA-specific exonuclease RecJ; COG: COG0608.
 
  
 0.586
dnaE
DNA polymerase III, alpha subunit; COG: COG0587.
    
 0.562
Your Current Organism:
Lactobacillus ultunensis
NCBI taxonomy Id: 525365
Other names: L. ultunensis DSM 16047, Lactobacillus ultunensis DSM 16047, Lactobacillus ultunensis str. DSM 16047, Lactobacillus ultunensis strain DSM 16047
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.